Compare Stocks › V vs VRTX
Visa Inc. (V) vs Vertex Pharmaceuticals Incorporated (VRTX)
V
Visa Inc.
$299.71
VS
VRTX
Vertex Pharmaceuticals Incorporated
$458.05
Rewards
V
- ★Visa Inc. has maintained ROIC above 15% for 4 consecutive years, indicating a durable competitive advantage.
- ★Gross margin of 97.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
- ★Visa Inc. scores 99/100 on the Economic Moat Score (Wide Moat), with roic consistency as the strongest competitive dimension.
VRTX
- ★Each dollar of retained earnings has created $5.82 of market value — management is an exceptional capital allocator.
- ★PEG ratio of 0.91 suggests the stock is undervalued relative to its growth rate — paying less than 1x for each unit of earnings growth.
- ★Altman Z-Score of 12.04 indicates very low bankruptcy risk — the company is firmly in the safe zone.
Risks
V
- ⚠Insiders have sold $3.9M worth of stock in the past 3 months — significant insider liquidation.
VRTX
- ⚠ROIC has declined by 5.3 percentage points over the observed period, which may signal competitive erosion.
- ⚠FCF yield of 2.2% is below 3%, meaning the market is pricing in substantial future growth to justify the current price.
- ⚠30 insider sales totaling $75.0M with no purchases in the past 3 months — insiders are reducing their exposure.
Key Valuation Metrics
Learn more →V
VRTX
Valuation
$22.03B
Free Cash Flow
$2.57B
3.81%
FCF Yield
2.21%
28.17
Trailing P/E
29.94
20.62
Forward P/E
20.87
Quality & Moat
37.25%
ROIC
18.14%
51.73%
ROE
21.18%
97.78%
Gross Margin
53.66%
1.62
PEG Ratio
0.91
Balance Sheet Safety
0.55
Debt / Equity
0.11
N/A
Interest Coverage
N/A
0.16
Net Debt / EBITDA
-0.94
0.89%
Dividend Yield
N/A
V: 6Ties: 2VRTX: 3
VVRTX
Historical Fundamentals
Learn more →V
Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.
VRTX
Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.
Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.
$1 Retained Earnings Test
Learn more →V
$5.50
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$44.47B
Δ Market Cap
+$244.54B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
VRTX
$5.82
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$7.04B
Δ Market Cap
+$40.93B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
Discounted Cash Flow (DCF) Analysis
Learn more →V
1.1% Margin of Safety
Price is 1.1% below estimated fair value
Current Price: $299.71
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
Fair Value: $303.16
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
VRTX
10.2% Margin of Safety
Price is 10.2% below estimated fair value
Current Price: $458.05
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
Fair Value: $510.34
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
Reverse DCF — Market-Implied Growth
Learn more →V
What growth rate is the market pricing in at $300?
+12.8%
Market-Implied Owner Earnings Growth
Standard FCF implies +11.5%
The market implies +12.8% Owner Earnings growth, roughly in line with history — reasonably priced.
Standard FCF implies +11.5%, reflecting ongoing growth investment.
VRTX
What growth rate is the market pricing in at $458?
+12.4%
Market-Implied Owner Earnings Growth
Standard FCF implies +18.3%
The market implies +12.4% Owner Earnings growth, above historical trends.
Standard FCF implies a demanding +18.3%, reflecting heavy growth investment.
Economic Moat Score
Learn more →V
99/100
Wide Moat
70+ Wide · 40-69 Narrow · <40 None
Wide moat with strength across all dimensions. ROIC Consistency is the standout factor.
Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
VRTX
65/100
Narrow Moat
70+ Wide · 40-69 Narrow · <40 None
Narrow moat with revenue predictability as the key competitive advantage. Improving margin stability would strengthen the moat.
Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
Forensic Accounting
Learn more →V
-2.50
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone
M-Score Trend
Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
VRTX
-2.21
Possible Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone
M-Score Trend
Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
Ownership Breakdown
Learn more →V
Insiders 0.6%Institutions 90.8%Retail & Other 8.7%
No. of Institutional Holders5,907
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
VRTX
Insiders 0.2%Institutions 97.7%Retail & Other 2.1%
No. of Institutional Holders2,318
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.
Insider Buying Activity
Learn more →V
0
Buys (3M)
0
Buys (12M)
No open market insider purchases found.
Open market purchases · includes direct & indirect ownership · excludes option exercises
VRTX
0
Buys (3M)
2
Buys (12M)
Total value (12M): $5.84M
KEWALRAMANI RESHMA
Chief Executive Officer
$3.90M
@ $389.58 · 2025-08-06
SACHS BRUCE I
Director
$1.95M
@ $389.68 · 2025-08-06
Open market purchases · includes direct & indirect ownership · excludes option exercises
Open market purchases · includes direct & indirect ownership · excludes option exercises.
Insider Selling Activity
Learn more →V
2
Sells (3M)
24
Sells (12M)
Total value (12M): $101.23M
CARNEY LLOYD A
Director
$201,253
@ $309.62 · 2026-03-11
MCINERNEY RYAN
Chief Executive Officer
$3.66M
@ $349.18 · 2026-01-02
MCINERNEY RYAN
Chief Executive Officer
$3.57M
@ $340.07 · 2025-12-11
ROTTENBERG JULIE B
General Counsel
$699,315
@ $345.00 · 2025-12-11
TANEJA RAJAT
Officer
$7.84M
@ $330.14 · 2025-12-02
FABARA PAUL D
Officer
$2.50M
@ $331.45 · 2025-12-02
TANEJA RAJAT
Officer
$2.08M
@ $330.00 · 2025-11-21
FABARA PAUL D
Officer
$707,917
@ $325.93 · 2025-11-21
CARNEY LLOYD A
Director
$302,832
@ $336.48 · 2025-11-04
MCINERNEY RYAN
Chief Executive Officer
$3.58M
@ $341.00 · 2025-11-03
MCINERNEY RYAN
Chief Executive Officer
$3.59M
@ $342.30 · 2025-10-01
MCINERNEY RYAN
Chief Executive Officer
$3.65M
@ $348.57 · 2025-09-02
ROTTENBERG JULIE B
General Counsel
$697,329
@ $344.02 · 2025-08-18
MCINERNEY RYAN
Chief Executive Officer
$3.60M
@ $343.13 · 2025-08-14
MCINERNEY RYAN
Chief Executive Officer
$3.05M
@ $353.82 · 2025-07-01
FABARA PAUL D
Officer
$4.36M
@ $375.00 · 2025-06-11
TANEJA RAJAT
President
$18.44M
@ $368.87 · 2025-06-05
FABARA PAUL D
Officer
$17.10M
@ $370.00 · 2025-06-05
MCINERNEY RYAN
Chief Executive Officer
$3.13M
@ $362.77 · 2025-06-02
FABARA PAUL D
Officer
$6.32M
@ $357.45 · 2025-05-12
FABARA PAUL D
Officer
$5.26M
@ $355.04 · 2025-05-08
MCINERNEY RYAN
Chief Executive Officer
$2.98M
@ $345.58 · 2025-05-01
ROTTENBERG JULIE B
General Counsel
$889,868
@ $345.58 · 2025-05-01
MCINERNEY RYAN
Chief Executive Officer
$3.02M
@ $350.44 · 2025-04-01
FABARA PAUL D
Officer
$13.40M
@ $340.41 · 2025-03-19
FABARA PAUL D
Officer
$12.88M
@ $327.20 · 2025-03-14
MCINERNEY RYAN
Chief Executive Officer
$3.13M
@ $363.00 · 2025-03-03
ANDRESKI PETER M
Officer
$815,314
@ $349.62 · 2025-02-07
MAHON TULLIER KELLY
Officer
$11.80M
@ $349.77 · 2025-02-07
MCINERNEY RYAN
Chief Executive Officer
$2.93M
@ $340.00 · 2025-02-03
ROTTENBERG JULIE B
General Counsel
$874,480
@ $340.00 · 2025-02-03
MCINERNEY RYAN
Chief Executive Officer
$2.74M
@ $317.78 · 2025-01-02
TANEJA RAJAT
Officer
$11.15M
@ $315.55 · 2024-12-13
MCINERNEY RYAN
Chief Executive Officer
$2.73M
@ $316.90 · 2024-12-02
FABARA PAUL D
Officer
$668,603
@ $307.97 · 2024-11-22
MCINERNEY RYAN
Chief Executive Officer
$2.49M
@ $288.49 · 2024-11-01
ROTTENBERG JULIE B
General Counsel
$741,996
@ $288.49 · 2024-11-01
MCINERNEY RYAN
Chief Executive Officer
$2.39M
@ $276.97 · 2024-10-01
MCINERNEY RYAN
Chief Executive Officer
$2.38M
@ $276.37 · 2024-09-03
MCINERNEY RYAN
Chief Executive Officer
$2.37M
@ $275.00 · 2024-08-29
ROTTENBERG JULIE B
General Counsel
$707,300
@ $275.00 · 2024-08-29
MAHON TULLIER KELLY
Officer
$10.12M
@ $267.64 · 2024-08-16
FABARA PAUL D
Officer
$7.01M
@ $277.15 · 2024-05-15
CARNEY LLOYD A
Director
$250,472
@ $275.55 · 2024-04-26
MCINERNEY RYAN
Chief Executive Officer
$2.30M
@ $280.36 · 2024-04-01
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
VRTX
30
Sells (3M)
40
Sells (12M)
Total value (12M): $146.21M
BOZIC CARMEN
Officer
$1.12M
@ $481.79 · 2026-03-13
MCKECHNIE DUNCAN
Officer
$1.31M
@ $498.42 · 2026-03-11
MCKECHNIE DUNCAN
Officer
$1.16M
@ $475.30 · 2026-03-04
LIU JOY
Officer
$442,396
@ $495.96 · 2026-03-02
BOZIC CARMEN
Officer
$1.12M
@ $480.31 · 2026-02-27
KEWALRAMANI RESHMA
Chief Executive Officer
$19.74M
@ $493.47 · 2026-02-27
AMBROSE KRISTEN
Officer
$172,560
@ $483.36 · 2026-02-26
ATKINSON EDWARD MORROW III
Chief Technology Officer
$324,882
@ $486.35 · 2026-02-25
MCKECHNIE DUNCAN
Officer
$2.39M
@ $487.65 · 2026-02-25
BUNNAGE MARK E.
Officer
$301,537
@ $486.35 · 2026-02-25
AMBROSE KRISTEN
Officer
$108,456
@ $486.35 · 2026-02-25
BILLER JONATHAN PRIM
Officer
$459,601
@ $486.35 · 2026-02-25
TATSIS OURANIA
Officer
$126,451
@ $486.35 · 2026-02-25
SACHDEV AMIT
Officer
$897,802
@ $486.35 · 2026-02-25
SACHDEV AMIT
Officer
$27.48M
@ $468.83 · 2026-02-19
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.38M
@ $484.93 · 2026-02-18
BUNNAGE MARK E.
Officer
$1.75M
@ $484.31 · 2026-02-18
AMBROSE KRISTEN
Officer
$1.06M
@ $484.87 · 2026-02-18
BILLER JONATHAN PRIM
Officer
$1.80M
@ $484.18 · 2026-02-18
TATSIS OURANIA
Officer
$472,395
@ $483.52 · 2026-02-18
BILLER JONATHAN PRIM
Officer
$493,012
@ $499.00 · 2026-02-13
TATSIS OURANIA
Officer
$749,985
@ $499.99 · 2026-02-13
BHATIA SANGEETA N
Director
$133,000
@ $500.00 · 2026-02-13
ATKINSON EDWARD MORROW III
Chief Technology Officer
$806,213
@ $460.43 · 2026-02-11
BUNNAGE MARK E.
Officer
$930,529
@ $460.43 · 2026-02-11
AMBROSE KRISTEN
Officer
$633,552
@ $460.43 · 2026-02-11
BILLER JONATHAN PRIM
Officer
$886,328
@ $460.43 · 2026-02-11
TATSIS OURANIA
Officer
$214,560
@ $460.43 · 2026-02-11
TATSIS OURANIA
Officer
$2.14M
@ $474.99 · 2026-01-07
WAGNER CHARLES F JR
Chief Operating Officer
$4.39M
@ $461.00 · 2026-01-06
BILLER JONATHAN PRIM
Officer
$155,803
@ $449.00 · 2025-12-03
TATSIS OURANIA
Officer
$2.02M
@ $449.99 · 2025-12-03
WAGNER CHARLES F JR
Chief Operating Officer
$6.38M
@ $456.00 · 2025-12-03
LEIDEN JEFFREY M
Officer and Director
$28.65M
@ $449.20 · 2025-12-03
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.09M
@ $434.58 · 2025-11-17
LEIDEN JEFFREY M
Officer and Director
$32.29M
@ $440.60 · 2025-11-14
BILLER JONATHAN PRIM
Officer
$280,522
@ $404.21 · 2025-10-02
BHATIA SANGEETA N
Director
$102,860
@ $386.69 · 2025-08-27
ALTSHULER DAVID
Officer
$22,084
@ $424.69 · 2025-05-15
BHATIA SANGEETA N
Director
$202,344
@ $505.86 · 2025-05-02
ALTSHULER DAVID
Officer
$1.65M
@ $510.00 · 2025-03-13
TATSIS OURANIA
Officer
$1.62M
@ $499.99 · 2025-03-10
ALTSHULER DAVID
Officer
$1.62M
@ $500.00 · 2025-03-10
WAGNER CHARLES F JR
Chief Financial Officer
$1.65M
@ $500.00 · 2025-03-10
TATSIS OURANIA
Officer
$1.97M
@ $485.49 · 2025-03-04
ALTSHULER DAVID
Officer
$1.58M
@ $490.00 · 2025-03-03
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.26M
@ $475.34 · 2025-02-27
TATSIS OURANIA
Officer
$251,930
@ $475.34 · 2025-02-27
ALTSHULER DAVID
Officer
$610,560
@ $480.00 · 2025-02-27
ATKINSON EDWARD MORROW III
Officer
$849,839
@ $480.95 · 2025-02-25
AMBROSE KRISTEN
Officer
$425,160
@ $480.95 · 2025-02-25
TATSIS OURANIA
Officer
$170,256
@ $480.95 · 2025-02-25
ALTSHULER DAVID
Officer
$407,846
@ $480.95 · 2025-02-25
ALTSHULER DAVID
Officer
$533,280
@ $480.00 · 2025-02-20
AMBROSE KRISTEN
Officer
$305,345
@ $455.06 · 2025-02-18
BILLER JONATHAN PRIM
Officer
$754,034
@ $455.06 · 2025-02-18
TATSIS OURANIA
Officer
$111,035
@ $455.06 · 2025-02-18
AMBROSE KRISTEN
Officer
$632,726
@ $459.83 · 2025-02-11
ATKINSON EDWARD MORROW III
Chief Technology Officer
$803,323
@ $459.83 · 2025-02-11
BILLER JONATHAN PRIM
Officer
$1.58M
@ $459.87 · 2025-02-11
TATSIS OURANIA
Officer
$142,547
@ $459.83 · 2025-02-11
ALTSHULER DAVID
Officer
$7,178
@ $478.53 · 2024-11-15
WAGNER CHARLES F JR
Chief Financial Officer
$1.55M
@ $518.27 · 2024-11-11
KEWALRAMANI RESHMA
Chief Executive Officer
$7.83M
@ $515.00 · 2024-11-08
BILLER JONATHAN PRIM
Officer
$461,198
@ $461.66 · 2024-10-02
BHATIA SANGEETA N
Director
$323,000
@ $500.00 · 2024-08-30
LEIDEN JEFFREY M
Officer and Director
$1.89M
@ $499.00 · 2024-08-30
BHATIA SANGEETA N
Director
$602,447
@ $466.29 · 2024-08-08
BOZIC CARMEN
Officer
$1.09M
@ $476.75 · 2024-08-07
SACHS BRUCE I
Director
$2.69M
@ $508.00 · 2024-08-01
KEWALRAMANI RESHMA
Chief Executive Officer
$7.68M
@ $505.00 · 2024-07-30
BOZIC CARMEN
Officer
$1.11M
@ $488.46 · 2024-07-24
KEWALRAMANI RESHMA
Chief Executive Officer
$7.56M
@ $497.00 · 2024-07-22
BOZIC CARMEN
Officer
$1.11M
@ $487.34 · 2024-07-10
BOZIC CARMEN
Officer
$1.08M
@ $471.72 · 2024-06-26
BOZIC CARMEN
Officer
$1.09M
@ $478.00 · 2024-06-12
ATKINSON EDWARD MORROW III
Chief Technology Officer
$3.48M
@ $478.00 · 2024-06-12
TATSIS OURANIA
Officer
$1.00M
@ $460.00 · 2024-06-03
WAGNER CHARLES F JR
Chief Financial Officer
$1.50M
@ $460.00 · 2024-06-03
TATSIS OURANIA
Officer
$2.03M
@ $441.99 · 2024-05-31
BOZIC CARMEN
Officer
$1.02M
@ $445.56 · 2024-05-29
WAGNER CHARLES F JR
Chief Financial Officer
$1.48M
@ $454.79 · 2024-05-28
KEWALRAMANI RESHMA
Chief Executive Officer
$715,205
@ $457.00 · 2024-05-24
SACHS BRUCE I
Director
$3.17M
@ $448.00 · 2024-05-22
KEWALRAMANI RESHMA
Chief Executive Officer
$6.80M
@ $447.00 · 2024-05-20
ARBUCKLE STUART A
Chief Operating Officer
$29,734
@ $430.93 · 2024-05-15
ALTSHULER DAVID
Officer
$23,270
@ $430.93 · 2024-05-15
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.
🎭 Mr. Market's Mood
Learn more →V
😨Fear(36/100)
"Market is pessimistic — investigate whether fears are temporary or structural"
Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
VRTX
😐Neutral(50/100)
"Market is pricing this stock without strong emotion in either direction"
Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
⚖️ Buffett Signal
Learn more →V
⚪Awaiting DCF Data
The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.
DCF Margin of Safety: N/AMr. Market's Mood: Fear (36)
VRTX
⚪Awaiting DCF Data
The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.
DCF Margin of Safety: N/AMr. Market's Mood: Neutral (50)