Compare StocksUNH vs VRTX

UnitedHealth Group Incorporated (UNH) vs Vertex Pharmaceuticals Incorporated (VRTX): Which Is the Better Buy in 2026?

As of 2026-06-19, UNH is fairly valued at $401, with a DCF intrinsic value of $376 and a margin of safety of -7%. VRTX is fairly valued at $452, with an intrinsic value of $454 and a margin of safety of 0%. Of the two, VRTX has the wider margin of safety.

UNH
UnitedHealth Group Incorporated
$400.96
VS
VRTX
Vertex Pharmaceuticals Incorporated
$451.63

Rewards

UNH
  • UnitedHealth Group Incorporated scores 73/100 on the Economic Moat Score (Wide Moat), with revenue predictability as the strongest competitive dimension.
VRTX
  • Altman Z-Score of 12.04 indicates very low bankruptcy risk — the company is firmly in the safe zone.
  • Net debt/EBITDA of -1.1x means the company holds more cash than debt — a net cash position.

Risks

UNH
  • ROIC has declined by 6.9 percentage points over the past 4 years, which may signal competitive erosion.
  • Gross margin of 18.8% is low, suggesting a competitive or commodity-like market with limited pricing power.
  • Free cash flow has declined at a 11.8% CAGR over the past 4 years — a concerning trend.
VRTX
  • FCF yield of 2.4% is below 3%, meaning the market is pricing in substantial future growth to justify the current price.
  • 10 insider sales totaling $7.9M with no purchases in the past 3 months — insiders are reducing their exposure.
  • Free cash flow has declined at a 6.6% CAGR over the past 4 years — a concerning trend.

Key Valuation Metrics

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UNH
VRTX
Valuation
$17.69B
Free Cash Flow
$2.78B
4.86%
FCF Yield
2.43%
30.17
Trailing P/E
26.79
19.18
Forward P/E
21.03
Quality & Moat
15.60%
ROIC
17.24%
12.18%
ROE
24.20%
18.80%
Gross Margin
54.39%
1.41
PEG Ratio
1.70
Balance Sheet Safety
0.44
Net Debt / Equity
Net cash
N/A
Interest Coverage
N/A
2.18
Net Debt / EBITDA
-1.06
2.21%
Dividend Yield
0.00%
UNH: 5Ties: 1VRTX: 6
UNHVRTX

Historical Fundamentals

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UNH

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

VRTX

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

$1 Retained Earnings Test

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UNH
$-7.37
created per $1 retained over 3 years
Market Cap Declined
Σ Retained
$26.63B
Δ Market Cap
$-196.16B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
VRTX
$5.82
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$7.04B
Δ Market Cap
+$40.93B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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UNH
6.6% Overvalued
Price is 6.6% above estimated fair value
Current Price: $400.96
Fair Value: $376.14
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
VRTX
0.4% Margin of Safety
Price is 0.4% below estimated fair value
Current Price: $451.63
Fair Value: $453.56
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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UNH

What growth rate is the market pricing in at $401?

+14.1%
Market-Implied Owner Earnings Growth
Standard FCF implies +9.8%

The market implies +14.1% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +9.8%, reflecting heavy growth investment.

VRTX

What growth rate is the market pricing in at $452?

+12.1%
Market-Implied Owner Earnings Growth
Standard FCF implies +16.9%

The market implies +12.1% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +16.9%, reflecting heavy growth investment.

Economic Moat Score

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UNH
73/100
Wide Moat
70+ Wide · 40-69 Narrow · <40 None

Wide moat driven primarily by revenue predictability. Margin Stability is the area most vulnerable to competitive pressure.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
VRTX
65/100
Narrow Moat
70+ Wide · 40-69 Narrow · <40 None

Narrow moat with revenue predictability as the key competitive advantage. Improving margin stability would strengthen the moat.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.

Forensic Accounting

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UNH
-2.45
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
VRTX
-2.06
Possible Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone
Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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UNH
Insiders 0.2%Institutions 85.9%Retail & Other 13.8%
No. of Institutional Holders4,020
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
VRTX
Insiders 0.2%Institutions 98.0%Retail & Other 1.8%
No. of Institutional Holders2,369
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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UNH
0
Buys (3M)
0
Buys (12M)
HEMSLEY STEPHEN J
Chief Executive Officer
$25.02M
@ $288.57 · 2025-05-16
REX JOHN F
President
$5.00M
@ $291.12 · 2025-05-16
GIL KRISTEN
Director
$1.00M
@ $271.17 · 2025-05-15
FLYNN TIMOTHY PATRICK
Director
$491,786
@ $320.80 · 2025-05-14
NOSEWORTHY JOHN H
Director
$93,647
@ $312.16 · 2025-05-14
FLYNN TIMOTHY PATRICK
Director
$511,575
@ $511.57 · 2025-01-17
Open market purchases · includes direct & indirect ownership · excludes option exercises
VRTX
0
Buys (3M)
2
Buys (12M)
Total value (12M): $5.84M
KEWALRAMANI RESHMA
Chief Executive Officer
$3.90M
@ $389.58 · 2025-08-06
SACHS BRUCE I
Director
$1.95M
@ $389.68 · 2025-08-06
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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UNH
1
Sells (3M)
1
Sells (12M)
Total value (12M): $284,000
CONWAY PATRICK HUGH M.D.
Officer
$284,000
@ $355.00 · 2026-04-23
CONWAY PATRICK HUGH M.D.
Chief Executive Officer
$179,645
@ $305.00 · 2025-06-10
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
VRTX
10
Sells (3M)
48
Sells (12M)
Total value (12M): $153.89M
BOZIC CARMEN
Officer
$785,250
@ $450.00 · 2026-06-05
LIU JOY
Officer
$364,245
@ $439.91 · 2026-06-01
BOZIC CARMEN
Officer
$888,300
@ $450.00 · 2026-05-29
BUNNAGE MARK E.
Officer
$14,964
@ $453.45 · 2026-05-15
BOZIC CARMEN
Officer
$613,971
@ $453.45 · 2026-05-15
BOZIC CARMEN
Officer
$3.14M
@ $450.00 · 2026-05-12
BHATIA SANGEETA N
Director
$134,746
@ $423.73 · 2026-05-04
LIU JOY
Officer
$469,222
@ $425.02 · 2026-05-01
LIU JOY
Officer
$439,288
@ $449.17 · 2026-04-01
BOZIC CARMEN
Officer
$1.05M
@ $450.95 · 2026-03-27
BOZIC CARMEN
Officer
$1.12M
@ $481.79 · 2026-03-13
MCKECHNIE DUNCAN
Officer
$1.31M
@ $498.42 · 2026-03-11
MCKECHNIE DUNCAN
Officer
$1.16M
@ $475.30 · 2026-03-04
LIU JOY
Officer
$442,396
@ $495.96 · 2026-03-02
BOZIC CARMEN
Officer
$1.12M
@ $480.31 · 2026-02-27
KEWALRAMANI RESHMA
Chief Executive Officer
$19.74M
@ $493.47 · 2026-02-27
AMBROSE KRISTEN
Officer
$172,560
@ $483.36 · 2026-02-26
ATKINSON EDWARD MORROW III
Chief Technology Officer
$324,882
@ $486.35 · 2026-02-25
MCKECHNIE DUNCAN
Officer
$2.39M
@ $487.65 · 2026-02-25
BUNNAGE MARK E.
Officer
$301,537
@ $486.35 · 2026-02-25
TATSIS OURANIA
Officer
$126,451
@ $486.35 · 2026-02-25
BILLER JONATHAN PRIM
Officer
$459,601
@ $486.35 · 2026-02-25
AMBROSE KRISTEN
Officer
$108,456
@ $486.35 · 2026-02-25
SACHDEV AMIT
Officer
$897,802
@ $486.35 · 2026-02-25
SACHDEV AMIT
Officer
$27.48M
@ $468.83 · 2026-02-19
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.38M
@ $484.93 · 2026-02-18
BUNNAGE MARK E.
Officer
$1.75M
@ $484.31 · 2026-02-18
TATSIS OURANIA
Officer
$472,395
@ $483.52 · 2026-02-18
BILLER JONATHAN PRIM
Officer
$1.80M
@ $484.18 · 2026-02-18
AMBROSE KRISTEN
Officer
$1.06M
@ $484.87 · 2026-02-18
TATSIS OURANIA
Officer
$749,985
@ $499.99 · 2026-02-13
BILLER JONATHAN PRIM
Officer
$493,012
@ $499.00 · 2026-02-13
BHATIA SANGEETA N
Director
$133,000
@ $500.00 · 2026-02-13
ATKINSON EDWARD MORROW III
Chief Technology Officer
$806,213
@ $460.43 · 2026-02-11
BUNNAGE MARK E.
Officer
$930,529
@ $460.43 · 2026-02-11
TATSIS OURANIA
Officer
$214,560
@ $460.43 · 2026-02-11
BILLER JONATHAN PRIM
Officer
$886,328
@ $460.43 · 2026-02-11
AMBROSE KRISTEN
Officer
$633,552
@ $460.43 · 2026-02-11
TATSIS OURANIA
Officer
$2.14M
@ $474.99 · 2026-01-07
WAGNER CHARLES F JR
Chief Operating Officer
$4.39M
@ $461.00 · 2026-01-06
TATSIS OURANIA
Officer
$2.02M
@ $449.99 · 2025-12-03
BILLER JONATHAN PRIM
Officer
$155,803
@ $449.00 · 2025-12-03
WAGNER CHARLES F JR
Chief Operating Officer
$6.38M
@ $456.00 · 2025-12-03
LEIDEN JEFFREY M
Officer and Director
$28.65M
@ $449.20 · 2025-12-03
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.09M
@ $434.58 · 2025-11-17
LEIDEN JEFFREY M
Officer and Director
$32.29M
@ $440.60 · 2025-11-14
BILLER JONATHAN PRIM
Officer
$280,522
@ $404.21 · 2025-10-02
BHATIA SANGEETA N
Director
$102,860
@ $386.69 · 2025-08-27
ALTSHULER DAVID
Officer
$22,084
@ $424.69 · 2025-05-15
BHATIA SANGEETA N
Director
$202,344
@ $505.86 · 2025-05-02
ALTSHULER DAVID
Officer
$1.65M
@ $510.00 · 2025-03-13
TATSIS OURANIA
Officer
$1.62M
@ $499.99 · 2025-03-10
ALTSHULER DAVID
Officer
$1.62M
@ $500.00 · 2025-03-10
WAGNER CHARLES F JR
Chief Financial Officer
$1.65M
@ $500.00 · 2025-03-10
TATSIS OURANIA
Officer
$1.97M
@ $485.49 · 2025-03-04
ALTSHULER DAVID
Officer
$1.58M
@ $490.00 · 2025-03-03
ATKINSON EDWARD MORROW III
Chief Technology Officer
$1.26M
@ $475.34 · 2025-02-27
TATSIS OURANIA
Officer
$251,930
@ $475.34 · 2025-02-27
ALTSHULER DAVID
Officer
$610,560
@ $480.00 · 2025-02-27
ATKINSON EDWARD MORROW III
Officer
$849,839
@ $480.95 · 2025-02-25
TATSIS OURANIA
Officer
$170,256
@ $480.95 · 2025-02-25
AMBROSE KRISTEN
Officer
$425,160
@ $480.95 · 2025-02-25
ALTSHULER DAVID
Officer
$407,846
@ $480.95 · 2025-02-25
ALTSHULER DAVID
Officer
$533,280
@ $480.00 · 2025-02-20
TATSIS OURANIA
Officer
$111,035
@ $455.06 · 2025-02-18
BILLER JONATHAN PRIM
Officer
$754,034
@ $455.06 · 2025-02-18
AMBROSE KRISTEN
Officer
$305,345
@ $455.06 · 2025-02-18
ATKINSON EDWARD MORROW III
Chief Technology Officer
$803,323
@ $459.83 · 2025-02-11
TATSIS OURANIA
Officer
$142,547
@ $459.83 · 2025-02-11
BILLER JONATHAN PRIM
Officer
$1.58M
@ $459.87 · 2025-02-11
AMBROSE KRISTEN
Officer
$632,726
@ $459.83 · 2025-02-11
ALTSHULER DAVID
Officer
$7,178
@ $478.53 · 2024-11-15
WAGNER CHARLES F JR
Chief Financial Officer
$1.55M
@ $518.27 · 2024-11-11
KEWALRAMANI RESHMA
Chief Executive Officer
$7.83M
@ $515.00 · 2024-11-08
BILLER JONATHAN PRIM
Officer
$461,198
@ $461.66 · 2024-10-02
BHATIA SANGEETA N
Director
$323,000
@ $500.00 · 2024-08-30
LEIDEN JEFFREY M
Officer and Director
$1.89M
@ $499.00 · 2024-08-30
BHATIA SANGEETA N
Director
$602,447
@ $466.29 · 2024-08-08
BOZIC CARMEN
Officer
$1.09M
@ $476.75 · 2024-08-07
SACHS BRUCE I
Director
$2.69M
@ $508.00 · 2024-08-01
KEWALRAMANI RESHMA
Chief Executive Officer
$7.68M
@ $505.00 · 2024-07-30
BOZIC CARMEN
Officer
$1.11M
@ $488.46 · 2024-07-24
KEWALRAMANI RESHMA
Chief Executive Officer
$7.56M
@ $497.00 · 2024-07-22
BOZIC CARMEN
Officer
$1.11M
@ $487.34 · 2024-07-10
BOZIC CARMEN
Officer
$1.08M
@ $471.72 · 2024-06-26
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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UNH
FearGreed
😏Greed(68/100)

"Market is optimistic — be cautious and ensure you have a margin of safety"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
VRTX
FearGreed
😐Neutral(57/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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UNH
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Greed (68)
VRTX
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (57)
View UNH Full AnalysisView VRTX Full Analysis

Frequently Asked Questions: UNH vs VRTX

Is UnitedHealth Group Incorporated or Vertex Pharmaceuticals Incorporated more undervalued in 2026?

Based on our discounted cash flow model, VRTX trades at a 0.4% margin of safety (intrinsic value $454 vs. price $452), compared to UNH's -6.6% margin of safety (intrinsic $376 vs. $401).

Which stock has a wider economic moat, UnitedHealth Group Incorporated or Vertex Pharmaceuticals Incorporated?

UNH scores 73/100 (Wide moat), while VRTX scores 65/100 (Narrow moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

Is UnitedHealth Group Incorporated in financial distress?

UNH's Altman Z-Score of 2.9 places it in the Grey zone, signaling elevated bankruptcy risk. VRTX scores 12.0 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

Which company has better free cash flow, UnitedHealth Group Incorporated or Vertex Pharmaceuticals Incorporated?

UnitedHealth Group Incorporated (UNH) generates a 4.9% free cash flow yield, compared to Vertex Pharmaceuticals Incorporated's 2.4%. A higher FCF yield means the business converts more of its market value into cash that can be returned to shareholders or reinvested.

Which stock has higher return on invested capital, UnitedHealth Group Incorporated or Vertex Pharmaceuticals Incorporated?

VRTX earns 17.2% ROIC versus UNH's 15.6%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.