Compare StocksPFE vs STE

Pfizer, Inc. (PFE) vs STERIS plc (STE): Which Is the Better Buy in 2026?

As of 2026-08-03, PFE is undervalued at $25, with a DCF intrinsic value of $127985960274 and a margin of safety of 100%. STE is overvalued at $228, with an intrinsic value of $186 and a margin of safety of -22%. Of the two, PFE has the wider margin of safety.

PFE
Pfizer, Inc.
$25.01
VS
STE
STERIS plc
$228.40

Rewards

PFE
  • Gross margin of 74.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Trailing P/E of 19.1x is 37% below the historical average of 30.4x — potentially undervalued relative to its own history.
STE
  • Free cash flow has grown at a 35.0% CAGR over the past 4 years, demonstrating strong earnings power growth.
  • Each dollar of retained earnings has created $5.76 of earning power — management is an exceptional capital allocator.
  • Management has timed buybacks well — 3 out of 4 years showed value-accretive repurchases.

Risks

PFE
  • ROIC has declined by 15.9 percentage points over the past 4 years, which may signal competitive erosion.
  • PEG ratio of 2.94 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
  • Altman Z-Score of 1.38 places the company in the distress zone — financial patterns resemble those of companies that experienced bankruptcy.
STE

    Key Valuation Metrics

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    PFE
    STE
    Valuation
    $12.38B
    Free Cash Flow
    $837.29M
    N/A
    FCF Yield
    3.76%
    19.09
    Trailing P/E
    28.80
    8.85
    Forward P/E
    18.70
    Quality & Moat
    10.19%
    ROIC
    10.12%
    8.31%
    ROE
    11.37%
    74.80%
    Gross Margin
    44.24%
    2.94
    PEG Ratio
    1.85
    Balance Sheet Safety
    0.57
    Net Debt / Equity
    0.23
    N/A
    Interest Coverage
    N/A
    2.03
    Net Debt / EBITDA
    1.03
    6.88%
    Dividend Yield
    1.13%
    PFE: 5Ties: 2STE: 4
    PFESTE

    Historical Fundamentals

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    PFE

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    STE

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    $1 Retained Earnings Test

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    PFE
    N/A
    Net losses over 3 years — test not applicable
    Company had negative cumulative retained earnings
    Σ Retained
    $-10.61B
    Δ Market Cap
    $-26.34
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
    STE
    $0.59
    created per $1 retained over 3 years
    Mediocre Allocator
    Σ Retained
    $1.11B
    Δ Market Cap
    +$653.9M
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Discounted Cash Flow (DCF) Analysis

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    PFE
    100.0% Margin of Safety
    Price is 100.0% below estimated fair value
    Current Price: $25.01
    Fair Value: $127985960274.09
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued
    STE
    22.5% Overvalued
    Price is 22.5% above estimated fair value
    Current Price: $228.40
    Fair Value: $186.47
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued

    Reverse DCF — Market-Implied Growth

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    PFE

    What growth rate is the market pricing in at $25?

    -14.2%
    Market-Implied Owner Earnings Growth
    Standard FCF implies -15.0%

    The market implies -14.2% Owner Earnings growth, above historical trends.

    Standard FCF implies a demanding -15.0%, reflecting heavy growth investment.

    STE

    What growth rate is the market pricing in at $228?

    +12.5%
    Market-Implied FCF Growth Rate

    Market below historical growth — potential opportunity.

    Economic Moat Score

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    PFE
    35/100
    No Moat
    70+ Wide · 40-69 Narrow · <40 None

    No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.
    STE
    63/100
    Narrow Moat
    70+ Wide · 40-69 Narrow · <40 None

    Narrow moat with revenue predictability as the key competitive advantage. Improving roic consistency would strengthen the moat.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.

    Forensic Accounting

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    PFE
    -2.53
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
    STE
    -2.67
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Ownership Breakdown

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    PFE
    Insiders 0.1%Institutions 69.5%Retail & Other 30.4%
    No. of Institutional Holders3,661
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
    STE
    Insiders 0.3%Institutions 99.9%
    No. of Institutional Holders1,216
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

    High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

    Insider Buying Activity

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    PFE
    0
    Buys (3M)
    0
    Buys (12M)
    BLAYLOCK RONALD E
    Director
    $499,072
    @ $25.65 · 2025-02-13
    GOTTLIEB SCOTT
    Director
    $28,240
    @ $28.24 · 2024-10-30
    Open market purchases · includes direct & indirect ownership · excludes option exercises
    STE
    0
    Buys (3M)
    0
    Buys (12M)
    No open market insider purchases found.
    Open market purchases · includes direct & indirect ownership · excludes option exercises

    Open market purchases · includes direct & indirect ownership · excludes option exercises.

    Insider Selling Activity

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    PFE
    1
    Sells (3M)
    1
    Sells (12M)
    Total value (12M): $51,400
    DAMICO JENNIFER B.
    Officer
    $51,400
    @ $25.70 · 2026-06-09
    DAMICO JENNIFER B.
    Officer
    $64,825
    @ $25.93 · 2025-03-04
    DAMICO JENNIFER B.
    Officer
    $147,714
    @ $28.66 · 2024-08-13
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
    STE
    0
    Sells (3M)
    0
    Sells (12M)
    No open market insider sales found.
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

    🎭 Mr. Market's Mood

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    PFE
    FearGreed
    😐Neutral(52/100)

    "Market is pricing this stock without strong emotion in either direction"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
    STE
    FearGreed
    😐Neutral(53/100)

    "Market is pricing this stock without strong emotion in either direction"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    ⚖️ Buffett Signal

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    PFE
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Neutral (52)
    STE
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Neutral (53)
    View PFE Full AnalysisView STE Full Analysis

    Frequently Asked Questions: PFE vs STE

    Is Pfizer, Inc. or STERIS plc more undervalued in 2026?

    Based on our discounted cash flow model, PFE trades at a 100.0% margin of safety (intrinsic value $127985960274 vs. price $25), compared to STE's -22.5% margin of safety (intrinsic $186 vs. $228).

    Which stock has a wider economic moat, Pfizer, Inc. or STERIS plc?

    STE scores 63/100 (Narrow moat), while PFE scores 35/100 (None moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

    Is Pfizer, Inc. in financial distress?

    PFE's Altman Z-Score of 1.4 places it in the Distress zone, signaling elevated bankruptcy risk. STE scores 5.2 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

    Which stock has higher return on invested capital, Pfizer, Inc. or STERIS plc?

    PFE earns 10.2% ROIC versus STE's 10.1%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

    Which dividend is safer, Pfizer, Inc.'s or STERIS plc's?

    STE's dividend earns a safety score of 94/100 (Very Safe), compared to PFE's 24/100 (Unsafe). STE has raised its dividend for 3 consecutive years.

    PFE vs STE: Which Is the Better Buy in 2026? | SafetyMargin.io