Compare StocksPFE vs SNPS

Pfizer Inc. (PFE) vs Synopsys, Inc. (SNPS): Which Is the Better Buy in 2026?

As of 2026-09-17, PFE is overvalued at $28, with a DCF intrinsic value of $22 and a margin of safety of -23%. SNPS is overvalued at $384, with an intrinsic value of $287 and a margin of safety of -33%. Of the two, PFE has the wider margin of safety.

PFE
Pfizer Inc.
$27.66
VS
SNPS
Synopsys, Inc.
$383.60

Rewards

PFE
  • Gross margin of 74.7% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Insiders have bought $3.0M worth of stock in the past 3 months — significant skin in the game.
SNPS
  • Gross margin of 82.9% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Each dollar of retained earnings has created $1.73 of earning power — management is creating shareholder value.

Risks

PFE
  • ROIC has declined by 15.9 percentage points over the past 4 years, which may signal competitive erosion.
  • FCF yield of 7.9% suggests reasonable valuation assuming continued moderate growth.
  • PEG ratio of 12.68 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
SNPS
  • ROIC has declined by 14.4 percentage points over the past 4 years, which may signal competitive erosion.
  • Share count has increased by 22% over the past 4 years, diluting existing shareholders.
  • Trailing P/E of 67.2x is 32% above the historical average of 51.0x — the stock trades at a premium to its own history.

Key Valuation Metrics

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PFE
SNPS
Valuation
$12.49B
Free Cash Flow
$3.43B
7.92%
FCF Yield
4.66%
36.39
Trailing P/E
67.18
9.55
Forward P/E
21.89
Quality & Moat
9.42%
ROIC
2.57%
5.01%
ROE
3.66%
74.72%
Gross Margin
82.92%
12.68
PEG Ratio
2.04
Balance Sheet Safety
0.61
Net Debt / Equity
0.23
N/A
Interest Coverage
N/A
2.04
Net Debt / EBITDA
3.49
6.26%
Dividend Yield
0.00%
PFE: 8Ties: 1SNPS: 3
PFESNPS

Historical Fundamentals

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PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

SNPS

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

$1 Retained Earnings Test

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PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-146.18B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
SNPS
$8.02
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$4.83B
Δ Market Cap
+$38.71B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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PFE
23.3% Overvalued
Price is 23.3% above estimated fair value
Current Price: $27.66
Fair Value: $22.43
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
SNPS
33.4% Overvalued
Price is 33.4% above estimated fair value
Current Price: $383.60
Fair Value: $287.46
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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PFE

What growth rate is the market pricing in at $28?

+6.2%
Market-Implied Owner Earnings Growth
Standard FCF implies +5.3%

The market implies +6.2% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +5.3%, reflecting heavy growth investment.

SNPS

What growth rate is the market pricing in at $384?

+18.5%
Market-Implied Owner Earnings Growth
Standard FCF implies +9.9%

The market implies +18.5% Owner Earnings growth, below historical trends — potential opportunity.

Standard FCF implies a more demanding +9.9%, reflecting heavy growth investment expected to generate future returns.

Economic Moat Score

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PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.
SNPS
66/100
Narrow Moat
70+ Wide · 40-69 Narrow · <40 None

Narrow moat with revenue predictability as the key competitive advantage. Improving margin stability would strengthen the moat.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.

Forensic Accounting

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PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
SNPS
-3.12
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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PFE
Insiders 0.1%Institutions 69.1%Retail & Other 30.8%
No. of Institutional Holders3,645
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
SNPS
Insiders 3.0%Institutions 93.1%Retail & Other 3.9%
No. of Institutional Holders2,111
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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PFE
3
Buys (3M)
3
Buys (12M)
Total value (12M): $2.96M
BOURLA ALBERT
Chief Executive Officer
$1.00M
@ $26.34 · 2026-08-12
BLAYLOCK RONALD E
Director
$998,821
@ $25.46 · 2026-08-05
BUCKLEY MORTIMER J.
Director
$960,369
@ $25.52 · 2026-08-05
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises
SNPS
0
Buys (3M)
0
Buys (12M)
PAINTER ROBERT G
Director
$148,904
@ $425.44 · 2025-09-11
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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PFE
1
Sells (3M)
2
Sells (12M)
Total value (12M): $134,661
DAMICO JENNIFER B.
Officer
$83,261
@ $25.40 · 2026-08-05
DAMICO JENNIFER B.
Officer
$51,400
@ $25.70 · 2026-06-09
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
SNPS
3
Sells (3M)
8
Sells (12M)
Total value (12M): $54.48M
GHAZI SASSINE E
Chief Executive Officer
$5.47M
@ $374.88 · 2026-09-15
DE GEUS AART J
Officer and Director
$21.38M
@ $430.68 · 2026-09-01
DE GEUS AART J
Officer and Director
$11.14M
@ $445.55 · 2026-08-28
GHAZI SASSINE E
Chief Executive Officer
$6.70M
@ $458.96 · 2026-06-15
LEE JANET
General Counsel
$132,500
@ $530.00 · 2026-01-12
LEE JANET
General Counsel
$127,500
@ $510.00 · 2026-01-07
GLASER SHELAGH M
Chief Financial Officer
$1.69M
@ $460.77 · 2025-12-19
KANKANWADI SUDHINDRA
Officer
$7.84M
@ $493.76 · 2025-09-22
GLASER SHELAGH M
Chief Financial Officer
$2.23M
@ $609.77 · 2025-09-05
GHAZI SASSINE E
Chief Executive Officer
$6.69M
@ $589.01 · 2025-09-02
MAHONEY RICHARD S
Officer
$4.25M
@ $471.21 · 2025-06-18
GLASER SHELAGH M
Chief Financial Officer
$3.55M
@ $485.72 · 2025-06-06
GHAZI SASSINE E
Chief Executive Officer
$5.20M
@ $457.93 · 2025-06-02
DE GEUS AART J
Officer and Director
$6.98M
@ $444.42 · 2025-03-06
GHAZI SASSINE E
Chief Executive Officer
$5.27M
@ $463.75 · 2025-03-03
MAHONEY RICHARD S
Officer
$10.54M
@ $506.01 · 2025-01-15
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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PFE
FearGreed
😐Neutral(60/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
SNPS
FearGreed
😨Fear(29/100)

"Market is pessimistic — investigate whether fears are temporary or structural"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (60)
SNPS
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Fear (29)
View PFE Full AnalysisView SNPS Full Analysis

Frequently Asked Questions: PFE vs SNPS

Is Pfizer Inc. or Synopsys, Inc. more undervalued in 2026?

Based on our discounted cash flow model, PFE trades at a -23.3% margin of safety (intrinsic value $22 vs. price $28), compared to SNPS's -33.4% margin of safety (intrinsic $287 vs. $384).

Which stock has a wider economic moat, Pfizer Inc. or Synopsys, Inc.?

SNPS scores 66/100 (Narrow moat), while PFE scores 35/100 (None moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

Is Pfizer Inc. in financial distress?

PFE's Altman Z-Score of 2.1 places it in the Grey zone, signaling elevated bankruptcy risk. SNPS scores 3.2 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

Which company has better free cash flow, Pfizer Inc. or Synopsys, Inc.?

Pfizer Inc. (PFE) generates a 7.9% free cash flow yield, compared to Synopsys, Inc.'s 4.7%. A higher FCF yield means the business converts more of its market value into cash that can be returned to shareholders or reinvested.

Which stock has higher return on invested capital, Pfizer Inc. or Synopsys, Inc.?

PFE earns 9.4% ROIC versus SNPS's 2.6%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.