Compare StocksMSFT vs TMO

Microsoft Corporation (MSFT) vs Thermo Fisher Scientific Inc (TMO): Which Is the Better Buy in 2026?

As of 2026-08-03, MSFT is undervalued at $465, with a DCF intrinsic value of $724 and a margin of safety of 36%. TMO is undervalued at $574, with an intrinsic value of $151245065994 and a margin of safety of 100%. Of the two, TMO has the wider margin of safety.

MSFT
Microsoft Corporation
$464.72
VS
TMO
Thermo Fisher Scientific Inc
$574.30

Rewards

MSFT
  • Microsoft Corporation has maintained ROIC above 15% for 4 consecutive years, indicating a durable competitive advantage.
  • Gross margin of 67.9% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Microsoft Corporation scores 84/100 on the Economic Moat Score (Wide Moat), with revenue predictability as the strongest competitive dimension.
TMO

    Risks

    MSFT
    • FCF yield of 1.9% is below 3%, meaning the market is pricing in substantial future growth to justify the current price.
    • Insiders have sold $10.5M worth of stock in the past 3 months — significant insider liquidation.
    TMO
    • Altman Z-Score of 1.54 places the company in the distress zone — financial patterns resemble those of companies that experienced bankruptcy.
    • 21 insider sales with no purchases over the past 12 months — a persistent pattern of insider selling.

    Key Valuation Metrics

    Learn more →
    MSFT
    TMO
    Valuation
    $66.99B
    Free Cash Flow
    $6.24B
    1.94%
    FCF Yield
    N/A
    25.90
    Trailing P/E
    30.86
    19.96
    Forward P/E
    20.88
    Quality & Moat
    20.70%
    ROIC
    7.20%
    34.04%
    ROE
    13.51%
    67.94%
    Gross Margin
    40.99%
    1.52
    PEG Ratio
    1.87
    Balance Sheet Safety
    0.12
    Net Debt / Equity
    0.73
    N/A
    Interest Coverage
    N/A
    0.27
    Net Debt / EBITDA
    3.28
    0.78%
    Dividend Yield
    0.33%
    MSFT: 9Ties: 2TMO: 0
    MSFTTMO

    Historical Fundamentals

    Learn more →
    MSFT

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    TMO

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    $1 Retained Earnings Test

    Learn more →
    MSFT
    $2.61
    created per $1 retained over 3 years
    Exceptional Value Creator
    Σ Retained
    $251.42B
    Δ Market Cap
    +$656.75B
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
    TMO
    $0.00
    created per $1 retained over 3 years
    Value Destroyer
    Σ Retained
    $17.29B
    Δ Market Cap
    +$28.76
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Discounted Cash Flow (DCF) Analysis

    Learn more →
    MSFT
    35.8% Margin of Safety
    Price is 35.8% below estimated fair value
    Current Price: $464.72
    Fair Value: $724.34
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued
    TMO
    100.0% Margin of Safety
    Price is 100.0% below estimated fair value
    Current Price: $574.30
    Fair Value: $151245065993.58
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued

    Reverse DCF — Market-Implied Growth

    Learn more →
    MSFT

    What growth rate is the market pricing in at $465?

    +11.4%
    Market-Implied Owner Earnings Growth
    Standard FCF implies +20.8%

    The market implies +11.4% Owner Earnings growth, below historical trends — potential opportunity.

    Standard FCF implies a more demanding +20.8%, reflecting heavy growth investment expected to generate future returns.

    TMO

    What growth rate is the market pricing in at $574?

    -12.7%
    Market-Implied Owner Earnings Growth
    Standard FCF implies -8.9%

    The market implies -12.7% Owner Earnings growth, below historical trends — potential opportunity.

    Standard FCF implies a more demanding -8.9%, reflecting heavy growth investment expected to generate future returns.

    Economic Moat Score

    Learn more →
    MSFT
    84/100
    Wide Moat
    70+ Wide · 40-69 Narrow · <40 None

    Wide moat driven primarily by revenue predictability. Reinvestment Efficiency is the area most vulnerable to competitive pressure.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
    TMO
    60/100
    Narrow Moat
    70+ Wide · 40-69 Narrow · <40 None

    Narrow moat with margin stability as the key competitive advantage. Improving roic consistency would strengthen the moat.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.

    Forensic Accounting

    Learn more →
    MSFT
    -2.58
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
    TMO
    -2.47
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Ownership Breakdown

    Learn more →
    MSFT
    Insiders 0.1%Institutions 75.8%Retail & Other 24.2%
    No. of Institutional Holders8,079
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
    TMO
    Insiders 0.1%Institutions 93.5%Retail & Other 6.4%
    No. of Institutional Holders3,509
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

    High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

    Insider Buying Activity

    Learn more →
    MSFT
    0
    Buys (3M)
    1
    Buys (12M)
    Total value (12M): $1.99M
    STANTON JOHN W.
    Director
    $1.99M
    @ $397.35 · 2026-02-18
    SMITH BRADFORD LEE
    President
    $1.45M
    @ $377.47 · 2025-04-23
    Open market purchases · includes direct & indirect ownership · excludes option exercises
    TMO
    0
    Buys (3M)
    0
    Buys (12M)
    CHAI NELSON J
    Director
    $11,038
    @ $551.90 · 2024-12-09
    Open market purchases · includes direct & indirect ownership · excludes option exercises

    Open market purchases · includes direct & indirect ownership · excludes option exercises.

    Insider Selling Activity

    Learn more →
    MSFT
    4
    Sells (3M)
    10
    Sells (12M)
    Total value (12M): $121.03M
    NUMOTO TAKESHI
    Officer
    $1.81M
    @ $402.84 · 2026-06-10
    NUMOTO TAKESHI
    Officer
    $1.03M
    @ $412.45 · 2026-06-08
    ALTHOFF JUDSON
    Officer
    $7.15M
    @ $460.99 · 2026-06-01
    COLEMAN AMY
    Officer
    $519,242
    @ $411.44 · 2026-05-14
    HOGAN KATHLEEN T
    Officer
    $5.05M
    @ $409.55 · 2026-03-06
    NUMOTO TAKESHI
    Officer
    $1.36M
    @ $478.72 · 2025-12-04
    ALTHOFF JUDSON
    Officer
    $6.27M
    @ $491.52 · 2025-12-02
    SMITH BRADFORD LEE
    President
    $19.97M
    @ $518.64 · 2025-11-03
    NADELLA SATYA
    Chief Executive Officer
    $75.32M
    @ $504.78 · 2025-09-03
    NUMOTO TAKESHI
    Officer
    $2.56M
    @ $527.32 · 2025-08-12
    NUMOTO TAKESHI
    Officer
    $1.39M
    @ $463.00 · 2025-06-03
    NUMOTO TAKESHI
    Officer
    $460,008
    @ $460.01 · 2025-05-30
    HOGAN KATHLEEN T
    Officer
    $9.76M
    @ $453.77 · 2025-05-21
    ALTHOFF JUDSON
    Officer
    $7.33M
    @ $458.18 · 2025-05-19
    COLEMAN AMY
    Officer
    $5.99M
    @ $452.04 · 2025-05-15
    SMITH BRADFORD LEE
    President
    $1.68M
    @ $438.44 · 2025-05-05
    SMITH BRADFORD LEE
    President
    $35.30M
    @ $435.84 · 2025-05-05
    NUMOTO TAKESHI
    Officer
    $1.12M
    @ $447.41 · 2024-12-09
    NUMOTO TAKESHI
    Officer
    $874,634
    @ $437.32 · 2024-12-04
    NUMOTO TAKESHI
    Officer
    $1.50M
    @ $428.76 · 2024-12-02
    ALTHOFF JUDSON
    Officer
    $10.43M
    @ $417.00 · 2024-11-22
    NUMOTO TAKESHI
    Officer
    $414,720
    @ $414.72 · 2024-11-22
    YOUNG CHRISTOPHER DAVID
    Officer
    $3.05M
    @ $423.66 · 2024-11-12
    NUMOTO TAKESHI
    Officer
    $1.03M
    @ $411.04 · 2024-09-10
    HOGAN KATHLEEN T
    Officer
    $7.16M
    @ $411.86 · 2024-09-10
    SMITH BRADFORD LEE
    President
    $16.10M
    @ $402.59 · 2024-09-09
    HOOD AMY E
    Chief Financial Officer
    $15.60M
    @ $410.55 · 2024-09-05
    NADELLA SATYA
    Chief Executive Officer
    $32.02M
    @ $408.63 · 2024-09-04
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
    TMO
    1
    Sells (3M)
    21
    Sells (12M)
    Total value (12M): $110.60M
    PETTITI GIANLUCA
    President
    $226,000
    @ $565.00 · 2026-07-27
    PETTITI GIANLUCA
    President
    $185,064
    @ $462.66 · 2026-04-27
    SHAFER MICHAEL D
    Officer
    $802,536
    @ $499.40 · 2026-03-11
    CASPER MARC N
    Chief Executive Officer
    $2.06M
    @ $514.82 · 2026-03-05
    CASPER MARC N
    Chief Executive Officer
    $5.08M
    @ $507.75 · 2026-03-04
    PETTITI GIANLUCA
    Officer
    $216,480
    @ $541.20 · 2026-02-09
    LAGARDE MICHEL
    Chief Operating Officer
    $12.42M
    @ $563.56 · 2025-12-04
    LAGARDE MICHEL
    Chief Operating Officer
    $36.13M
    @ $582.68 · 2025-12-03
    LOWERY FREDERICK M.
    Officer
    $8.15M
    @ $589.81 · 2025-12-02
    SHAFER MICHAEL D
    Officer
    $6.43M
    @ $600.00 · 2025-11-25
    LAGARDE MICHEL
    Chief Operating Officer
    $2.76M
    @ $594.42 · 2025-11-13
    BRITT LISA P
    Officer
    $622,136
    @ $588.59 · 2025-11-12
    PETTITI GIANLUCA
    Officer
    $1.73M
    @ $580.00 · 2025-11-10
    BRITT LISA P
    Officer
    $5.84M
    @ $571.62 · 2025-11-07
    CASPER MARC N
    Chief Executive Officer
    $13.91M
    @ $571.33 · 2025-10-27
    PETTITI GIANLUCA
    Officer
    $229,660
    @ $574.15 · 2025-10-24
    CASPER MARC N
    Chief Executive Officer
    $200,201
    @ $500.50 · 2025-09-05
    HOLMES JOSEPH R.
    Officer
    $189,662
    @ $492.63 · 2025-08-29
    CASPER MARC N
    Chief Executive Officer
    $5.01M
    @ $500.96 · 2025-08-22
    CASPER MARC N
    Chief Executive Officer
    $248,046
    @ $500.09 · 2025-08-20
    CASPER MARC N
    Chief Executive Officer
    $8.15M
    @ $452.99 · 2025-08-07
    PETTITI GIANLUCA
    Officer
    $191,992
    @ $479.98 · 2025-07-25
    PETTITI GIANLUCA
    Officer
    $164,444
    @ $411.11 · 2025-05-12
    PETTITI GIANLUCA
    Officer
    $128,979
    @ $429.93 · 2025-04-28
    BOXER MICHAEL A
    General Counsel
    $2.01M
    @ $532.59 · 2025-03-10
    CASPER MARC N
    Chief Executive Officer
    $9.33M
    @ $518.16 · 2025-03-05
    SHAFER MICHAEL D
    Officer
    $945,038
    @ $530.92 · 2025-03-03
    LOWERY FREDERICK M.
    Officer
    $9.73M
    @ $531.81 · 2025-02-24
    CHAI NELSON J
    Director
    $8,449
    @ $528.06 · 2025-02-19
    PETTITI GIANLUCA
    Officer
    $175,677
    @ $585.59 · 2025-02-04
    WILLIAMSON STEPHEN
    Chief Financial Officer
    $11.58M
    @ $589.36 · 2025-02-04
    CASPER MARC N
    Chief Executive Officer
    $10.62M
    @ $531.23 · 2024-12-03
    CASPER MARC N
    Chief Executive Officer
    $3.26M
    @ $557.89 · 2024-11-01
    CASPER MARC N
    Chief Executive Officer
    $11.01M
    @ $550.51 · 2024-10-31
    CASPER MARC N
    Chief Executive Officer
    $11.05M
    @ $552.46 · 2024-10-29
    BOXER MICHAEL A
    General Counsel
    $1.12M
    @ $560.16 · 2024-10-25
    PETTITI GIANLUCA
    Officer
    $168,048
    @ $560.16 · 2024-10-25
    CASPER MARC N
    Chief Executive Officer
    $12.17M
    @ $608.45 · 2024-09-04
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

    🎭 Mr. Market's Mood

    Learn more →
    MSFT
    FearGreed
    😐Neutral(57/100)

    "Market is pricing this stock without strong emotion in either direction"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
    TMO
    FearGreed
    😏Greed(61/100)

    "Market is optimistic — be cautious and ensure you have a margin of safety"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    ⚖️ Buffett Signal

    Learn more →
    MSFT
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Neutral (57)
    TMO
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Greed (61)
    View MSFT Full AnalysisView TMO Full Analysis

    Frequently Asked Questions: MSFT vs TMO

    Is Microsoft Corporation or Thermo Fisher Scientific Inc more undervalued in 2026?

    Based on our discounted cash flow model, TMO trades at a 100.0% margin of safety (intrinsic value $151245065994 vs. price $574), compared to MSFT's 35.8% margin of safety (intrinsic $724 vs. $465).

    Which stock has a wider economic moat, Microsoft Corporation or Thermo Fisher Scientific Inc?

    MSFT scores 84/100 (Wide moat), while TMO scores 60/100 (Narrow moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

    Is Thermo Fisher Scientific Inc in financial distress?

    TMO's Altman Z-Score of 1.5 places it in the Distress zone, signaling elevated bankruptcy risk. MSFT scores 8.3 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

    Which stock has higher return on invested capital, Microsoft Corporation or Thermo Fisher Scientific Inc?

    MSFT earns 20.7% ROIC versus TMO's 7.2%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

    Which dividend is safer, Microsoft Corporation's or Thermo Fisher Scientific Inc's?

    TMO's dividend earns a safety score of 94/100 (Very Safe), compared to MSFT's 94/100 (Very Safe). TMO has raised its dividend for 3 consecutive years.