Compare StocksMSCI vs PFE

MSCI Inc. (MSCI) vs Pfizer, Inc. (PFE): Which Is the Better Buy in 2026?

As of 2026-08-03, MSCI is overvalued at $572, with a DCF intrinsic value of $474 and a margin of safety of -21%. PFE is undervalued at $25, with an intrinsic value of $127985960274 and a margin of safety of 100%. Of the two, PFE has the wider margin of safety.

MSCI
MSCI Inc.
$572.24
VS
PFE
Pfizer, Inc.
$25.01

Rewards

MSCI
  • MSCI Inc. has maintained ROIC above 15% for 4 consecutive years, indicating a durable competitive advantage.
  • Gross margin of 83.0% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • MSCI Inc. scores 99/100 on the Economic Moat Score (Wide Moat), with roic consistency as the strongest competitive dimension.
PFE
  • Gross margin of 74.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Trailing P/E of 19.1x is 37% below the historical average of 30.4x — potentially undervalued relative to its own history.

Risks

MSCI
  • FCF yield of 2.9% is below 3%, meaning the market is pricing in substantial future growth to justify the current price.
  • PEG ratio of 2.24 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
PFE
  • ROIC has declined by 15.9 percentage points over the past 4 years, which may signal competitive erosion.
  • PEG ratio of 2.94 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
  • Altman Z-Score of 1.38 places the company in the distress zone — financial patterns resemble those of companies that experienced bankruptcy.

Key Valuation Metrics

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MSCI
PFE
Valuation
$1.19B
Free Cash Flow
$12.38B
2.87%
FCF Yield
N/A
31.25
Trailing P/E
19.09
25.46
Forward P/E
8.85
Quality & Moat
22.66%
ROIC
10.19%
N/A
ROE
8.31%
82.97%
Gross Margin
74.80%
2.24
PEG Ratio
2.94
Balance Sheet Safety
N/A
Net Debt / Equity
0.57
N/A
Interest Coverage
N/A
3.16
Net Debt / EBITDA
2.03
1.43%
Dividend Yield
6.88%
MSCI: 3Ties: 1PFE: 5
MSCIPFE

Historical Fundamentals

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MSCI

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

$1 Retained Earnings Test

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MSCI
$2.56
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$1.95B
Δ Market Cap
+$5.01B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-26.34
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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MSCI
20.7% Overvalued
Price is 20.7% above estimated fair value
Current Price: $572.24
Fair Value: $474.23
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
PFE
100.0% Margin of Safety
Price is 100.0% below estimated fair value
Current Price: $25.01
Fair Value: $127985960274.09
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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MSCI

What growth rate is the market pricing in at $572?

+16.1%
Market-Implied Owner Earnings Growth
Standard FCF implies +17.1%

The market implies +16.1% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +17.1%, reflecting heavy growth investment.

PFE

What growth rate is the market pricing in at $25?

-14.2%
Market-Implied Owner Earnings Growth
Standard FCF implies -15.0%

The market implies -14.2% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding -15.0%, reflecting heavy growth investment.

Economic Moat Score

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MSCI
99/100
Wide Moat
70+ Wide · 40-69 Narrow · <40 None

Wide moat with strength across all dimensions. ROIC Consistency is the standout factor.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

Forensic Accounting

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MSCI
-2.74
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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MSCI
Insiders 3.6%Institutions 93.7%Retail & Other 2.7%
No. of Institutional Holders1,557
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
PFE
Insiders 0.1%Institutions 69.5%Retail & Other 30.4%
No. of Institutional Holders3,661
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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MSCI
1
Buys (3M)
4
Buys (12M)
Total value (12M): $14.51M
FERNANDEZ HENRY A
Chief Executive Officer
$2.25M
@ $562.40 · 2026-05-15
ASHE ROBERT GERARD
Director
$2.00M
@ $543.21 · 2026-02-18
FERNANDEZ HENRY A
Chief Executive Officer
$3.56M
@ $523.56 · 2026-02-17
FERNANDEZ HENRY A
Chief Executive Officer
$6.70M
@ $536.14 · 2025-12-05
FERNANDEZ HENRY A
Chief Executive Officer
$6.73M
@ $542.87 · 2025-07-25
FERNANDEZ HENRY A
Chief Executive Officer
$3.04M
@ $574.51 · 2025-02-24
FERNANDEZ HENRY A
Chief Executive Officer
$1.78M
@ $612.80 · 2024-12-05
Open market purchases · includes direct & indirect ownership · excludes option exercises
PFE
0
Buys (3M)
0
Buys (12M)
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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MSCI
1
Sells (3M)
5
Sells (12M)
Total value (12M): $7.04M
WIECHMANN ANDREW CRAIG
Chief Financial Officer
$272,052
@ $604.56 · 2026-06-10
MUNARI ALVISE J.
Officer
$5.92M
@ $592.04 · 2026-04-24
WIECHMANN ANDREW CRAIG
Chief Financial Officer
$252,000
@ $560.00 · 2026-03-17
WIECHMANN ANDREW CRAIG
Chief Financial Officer
$247,500
@ $550.00 · 2025-12-11
GUTOWSKI ROBERT J
General Counsel
$348,454
@ $558.42 · 2025-11-24
PETTIT CARROLL DOUGLAS BAER
President
$2.82M
@ $563.62 · 2025-06-05
PETTIT CARROLL DOUGLAS BAER
President
$2.76M
@ $552.59 · 2025-05-05
PETTIT CARROLL DOUGLAS BAER
President
$2.62M
@ $524.25 · 2025-04-04
PETTIT CARROLL DOUGLAS BAER
President
$2.84M
@ $568.36 · 2025-03-05
GUTOWSKI ROBERT J
General Counsel
$1.04M
@ $575.00 · 2024-08-28
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
PFE
1
Sells (3M)
1
Sells (12M)
Total value (12M): $51,400
DAMICO JENNIFER B.
Officer
$51,400
@ $25.70 · 2026-06-09
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
DAMICO JENNIFER B.
Officer
$147,714
@ $28.66 · 2024-08-13
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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MSCI
FearGreed
😐Neutral(48/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
PFE
FearGreed
😐Neutral(52/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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MSCI
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (48)
PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (52)
View MSCI Full AnalysisView PFE Full Analysis

Frequently Asked Questions: MSCI vs PFE

Is MSCI Inc. or Pfizer, Inc. more undervalued in 2026?

Based on our discounted cash flow model, PFE trades at a 100.0% margin of safety (intrinsic value $127985960274 vs. price $25), compared to MSCI's -20.7% margin of safety (intrinsic $474 vs. $572).

Which stock has a wider economic moat, MSCI Inc. or Pfizer, Inc.?

MSCI scores 99/100 (Wide moat), while PFE scores 35/100 (None moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

Is Pfizer, Inc. in financial distress?

PFE's Altman Z-Score of 1.4 places it in the Distress zone, signaling elevated bankruptcy risk. MSCI scores 5.9 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

Which stock has higher return on invested capital, MSCI Inc. or Pfizer, Inc.?

MSCI earns 22.7% ROIC versus PFE's 10.2%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

Which dividend is safer, MSCI Inc.'s or Pfizer, Inc.'s?

MSCI's dividend earns a safety score of 94/100 (Very Safe), compared to PFE's 24/100 (Unsafe). MSCI has raised its dividend for 3 consecutive years.

MSCI vs PFE: Which Is the Better Buy in 2026? | SafetyMargin.io