Compare StocksINCY vs PFE

Incyte Corporation (INCY) vs Pfizer Inc. (PFE)

INCY
Incyte Corporation
$92.95
VS
PFE
Pfizer Inc.
$27.41

Rewards

INCY
  • Free cash flow has grown at a 14.2% CAGR over the past 4 years, demonstrating strong earnings power growth.
  • Share count has been reduced by 11% over the past 4 years through buybacks, increasing each share's claim on earnings.
  • Trailing P/E of 14.5x is 89% below the historical average of 130.7x — potentially undervalued relative to its own history.
PFE
  • Gross margin of 75.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Dividend yield of 6.28% with a consistent or growing payout over the past 4 years.
  • FCF yield of 8.6% is historically attractive — the business generates significant cash relative to its price.

Risks

INCY
  • FCF yield of 7.2% suggests reasonable valuation assuming continued moderate growth.
  • Insiders have sold $4.7M worth of stock in the past 3 months — significant insider liquidation.
PFE
  • ROIC has declined by 13.9 percentage points over the observed period, which may signal competitive erosion.
  • Free cash flow has declined at a 29.6% CAGR over the past 4 years — a concerning trend.

Key Valuation Metrics

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INCY
PFE
Valuation
$1.33B
Free Cash Flow
$13.43B
7.19%
FCF Yield
8.61%
14.50
Trailing P/E
20.15
10.75
Forward P/E
9.69
Quality & Moat
19.89%
ROIC
7.67%
24.90%
ROE
8.96%
52.88%
Gross Margin
75.81%
0.33
PEG Ratio
N/A
Balance Sheet Safety
0.01
Debt / Equity
0.78
N/A
Interest Coverage
N/A
-2.45
Net Debt / EBITDA
2.10
N/A
Dividend Yield
6.28%
INCY: 5Ties: 1PFE: 4
INCYPFE

Historical Fundamentals

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INCY

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

$1 Retained Earnings Test

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INCY
$0.89
created per $1 retained over 3 years
Mediocre Allocator
Σ Retained
$1.92B
Δ Market Cap
+$1.71B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-146.18B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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INCY
62.4% Margin of Safety
Price is 62.4% below estimated fair value
Current Price: $92.95
Fair Value: $247.14
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
PFE
140.2% Overvalued
Price is 140.2% above estimated fair value
Current Price: $27.41
Fair Value: $11.41
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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INCY

What growth rate is the market pricing in at $93?

+0.3%
Market-Implied Owner Earnings Growth
Standard FCF implies -0.2%

The market implies +0.3% Owner Earnings growth, below historical trends — potential opportunity.

Standard FCF implies a more demanding -0.2%, reflecting heavy growth investment expected to generate future returns.

PFE

What growth rate is the market pricing in at $27?

+11.8%
Market-Implied Owner Earnings Growth
Standard FCF implies +4.3%

The market implies +11.8% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +4.3%, reflecting heavy growth investment.

Economic Moat Score

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INCY
64/100
Narrow Moat
70+ Wide · 40-69 Narrow · <40 None

Narrow moat with reinvestment efficiency as the key competitive advantage. Improving margin stability would strengthen the moat.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

Forensic Accounting

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INCY
-2.43
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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INCY
Insiders 1.9%Institutions 104.7%
No. of Institutional Holders1,222
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
PFE
Insiders 0.1%Institutions 67.7%Retail & Other 32.2%
No. of Institutional Holders3,693
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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INCY
0
Buys (3M)
0
Buys (12M)
No open market insider purchases found.
Open market purchases · includes direct & indirect ownership · excludes option exercises
PFE
0
Buys (3M)
0
Buys (12M)
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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INCY
3
Sells (3M)
31
Sells (12M)
Total value (12M): $38.32M
CAGNONI PABLO J
Officer
$1.88M
@ $100.91 · 2026-02-19
ISSA MOHAMED KHAIRIE
Officer
$1.18M
@ $109.07 · 2026-01-07
STEIN STEVEN H.
Officer
$1.59M
@ $101.70 · 2026-01-05
TRAY THOMAS R
Officer
$336,350
@ $99.69 · 2025-12-19
MORRISSEY MICHAEL JAMES
Officer
$5.68M
@ $97.29 · 2025-12-17
MAYES PATRICK A
Officer
$554,965
@ $95.55 · 2025-12-11
STEIN STEVEN H.
Officer
$2.32M
@ $102.56 · 2025-12-02
TRAY THOMAS R
Officer
$79,038
@ $102.78 · 2025-11-24
DENTON SHEILA A
General Counsel
$29,012
@ $104.36 · 2025-11-17
HOPPENOT HERVE
Director
$19.77M
@ $105.46 · 2025-11-10
STEIN STEVEN H.
Officer
$534,813
@ $102.20 · 2025-11-05
DENTON SHEILA A
General Counsel
$60,613
@ $101.36 · 2025-11-04
HEESON LEE
Officer
$289,017
@ $94.02 · 2025-11-03
DENTON SHEILA A
General Counsel
$23,581
@ $85.13 · 2025-10-15
DENTON SHEILA A
General Counsel
$351,978
@ $85.85 · 2025-10-03
DENTON SHEILA A
General Counsel
$23,116
@ $83.15 · 2025-09-16
DENTON SHEILA A
General Counsel
$50,812
@ $84.97 · 2025-09-02
DENTON SHEILA A
General Counsel
$24,046
@ $86.81 · 2025-08-15
DENTON SHEILA A
General Counsel
$45,310
@ $75.77 · 2025-08-04
STEIN STEVEN H.
Officer
$251,786
@ $67.94 · 2025-07-21
DENTON SHEILA A
General Counsel
$286,296
@ $69.57 · 2025-07-16
IYENGAR VIJAY K
Officer
$67,198
@ $68.36 · 2025-07-16
FLANNELLY BARRY P.
Officer
$91,602
@ $68.36 · 2025-07-16
IYENGAR VIJAY K
Officer
$82,225
@ $69.86 · 2025-07-15
FLANNELLY BARRY P.
Officer
$83,273
@ $69.86 · 2025-07-15
STEIN STEVEN H.
Officer
$1.02M
@ $68.47 · 2025-07-14
IYENGAR VIJAY K
Officer
$587,275
@ $68.15 · 2025-07-03
FLANNELLY BARRY P.
Officer
$743,039
@ $68.15 · 2025-07-03
DENTON SHEILA A
General Counsel
$41,097
@ $68.61 · 2025-07-02
DENTON SHEILA A
General Counsel
$122,060
@ $68.00 · 2025-06-03
TRAY THOMAS R
Officer
$105,516
@ $65.38 · 2025-06-02
FLANNELLY BARRY P.
Officer
$1.34M
@ $67.69 · 2025-03-14
DENTON SHEILA A
General Counsel
$41,924
@ $69.99 · 2025-03-04
DENTON SHEILA A
General Counsel
$1.04M
@ $74.07 · 2025-02-26
STEIN STEVEN H.
Officer
$897,867
@ $72.69 · 2025-01-21
TRAY THOMAS R
Officer
$90,968
@ $69.98 · 2024-12-16
IYENGAR VIJAY K
Officer
$455,544
@ $75.38 · 2024-11-29
FLANNELLY BARRY P.
Officer
$293,210
@ $79.68 · 2024-11-06
TRAY THOMAS R
Officer
$60,209
@ $63.11 · 2024-09-13
DICKINSON JONATHAN ELLIOTT
Officer
$526,948
@ $62.36 · 2024-09-12
STEIN STEVEN H.
Officer
$703,793
@ $60.63 · 2024-08-12
IYENGAR VIJAY K
Officer
$1.09M
@ $70.00 · 2024-07-25
FLANNELLY BARRY P.
Officer
$83,832
@ $64.19 · 2024-07-16
FLANNELLY BARRY P.
Officer
$488,880
@ $60.00 · 2024-07-09
FLANNELLY BARRY P.
Officer
$1.15M
@ $60.00 · 2024-06-12
TRAY THOMAS R
Officer
$64,389
@ $58.91 · 2024-06-06
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
PFE
0
Sells (3M)
0
Sells (12M)
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
DAMICO JENNIFER B.
Officer
$147,714
@ $28.66 · 2024-08-13
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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INCY
FearGreed
😐Neutral(43/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
PFE
FearGreed
😏Greed(64/100)

"Market is optimistic — be cautious and ensure you have a margin of safety"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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INCY
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (43)
PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Greed (64)
View INCY Full AnalysisView PFE Full Analysis