Compare Stocks › GOOGL vs VRTX

Alphabet Inc. (GOOGL) vs Vertex Pharmaceuticals Incorporated (VRTX): Which Is the Better Buy in 2026?

As of 2026-11-01, GOOGL is overvalued at $280, with a DCF intrinsic value of $8 and a margin of safety of -3448%. VRTX is overvalued at $559, with an intrinsic value of $380 and a margin of safety of -47%. Of the two, VRTX has the wider margin of safety.

GOOGL
Alphabet Inc.
$279.84
VS
VRTX
Vertex Pharmaceuticals Incorporated
$558.88

Rewards

GOOGL
  • ★Alphabet Inc. has maintained ROIC above 15% for 4 consecutive years, indicating a durable competitive advantage.
  • ★Gross margin of 60.9% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • ★Alphabet Inc. scores 89/100 on the Economic Moat Score (Wide Moat), with roic consistency as the strongest competitive dimension.
VRTX
  • ★Altman Z-Score of 12.04 indicates very low bankruptcy risk — the company is firmly in the safe zone.
  • ★Net debt/EBITDA of -1.2x means the company holds more cash than debt — a net cash position.

Risks

GOOGL
    VRTX
    • ⚠FCF yield of 1.9% is below 3%, meaning the market is pricing in substantial future growth to justify the current price.
    • ⚠PEG ratio of 2.18 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
    • ⚠52 insider sales with no purchases over the past 12 months — a persistent pattern of insider selling.

    Key Valuation Metrics

    Learn more →
    GOOGL
    VRTX
    Valuation
    $-1.16B
    Free Cash Flow
    $2.63B
    -0.03%
    FCF Yield
    1.86%
    14.61
    Trailing P/E
    32.55
    18.49
    Forward P/E
    27.37
    Quality & Moat
    14.30%
    ROIC
    17.03%
    44.29%
    ROE
    23.54%
    60.86%
    Gross Margin
    54.96%
    0.98
    PEG Ratio
    2.18
    Balance Sheet Safety
    Net cash
    Net Debt / Equity
    Net cash
    N/A
    Interest Coverage
    N/A
    -0.62
    Net Debt / EBITDA
    -1.15
    0.31%
    Dividend Yield
    0.00%
    GOOGL: 6Ties: 1VRTX: 5
    GOOGLVRTX

    Historical Fundamentals

    Learn more →
    GOOGL

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    VRTX

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    $1 Retained Earnings Test

    Learn more →
    GOOGL
    $9.18
    created per $1 retained over 3 years
    Exceptional Value Creator
    Σ Retained
    $288.67B
    Δ Market Cap
    +$2.65T
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
    VRTX
    $5.82
    created per $1 retained over 3 years
    Exceptional Value Creator
    Σ Retained
    $7.04B
    Δ Market Cap
    +$40.93B
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Discounted Cash Flow (DCF) Analysis

    Learn more →
    GOOGL
    3447.8% Overvalued
    Price is 3447.8% above estimated fair value
    Current Price: $279.84
    Fair Value: $7.89
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued
    VRTX
    47.1% Overvalued
    Price is 47.1% above estimated fair value
    Current Price: $558.88
    Fair Value: $379.92
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued

    Reverse DCF — Market-Implied Growth

    Learn more →
    GOOGL

    Requires positive FCF to compute implied growth rate.

    VRTX

    What growth rate is the market pricing in at $559?

    +15.1%
    Market-Implied Owner Earnings Growth
    Standard FCF implies +20.6%

    The market implies +15.1% Owner Earnings growth, above historical trends.

    Standard FCF implies a demanding +20.6%, reflecting heavy growth investment.

    Economic Moat Score

    Learn more →
    GOOGL
    89/100
    Wide Moat
    70+ Wide · 40-69 Narrow · <40 None

    Wide moat driven primarily by roic consistency. Reinvestment Efficiency is the area most vulnerable to competitive pressure.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
    VRTX
    65/100
    Narrow Moat
    70+ Wide · 40-69 Narrow · <40 None

    Narrow moat with revenue predictability as the key competitive advantage. Improving margin stability would strengthen the moat.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.

    Forensic Accounting

    Learn more →
    GOOGL
    -2.92
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
    VRTX
    -2.06
    Possible Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone
    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Ownership Breakdown

    Learn more →
    GOOGL
    Insiders 1.6%Institutions 80.8%Retail & Other 17.6%
    No. of Institutional Holders7,451
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
    VRTX
    Insiders 0.2%Institutions 98.1%Retail & Other 1.7%
    No. of Institutional Holders2,464
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

    High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

    Insider Buying Activity

    Learn more →
    GOOGL
    0
    Buys (3M)
    0
    Buys (12M)
    No open market insider purchases found.
    Open market purchases · includes direct & indirect ownership · excludes option exercises
    VRTX
    0
    Buys (3M)
    0
    Buys (12M)
    KEWALRAMANI RESHMA
    Chief Executive Officer
    $3.90M
    @ $389.58 · 2025-08-06
    SACHS BRUCE I
    Director
    $1.95M
    @ $389.68 · 2025-08-06
    Open market purchases · includes direct & indirect ownership · excludes option exercises

    Open market purchases · includes direct & indirect ownership · excludes option exercises.

    Insider Selling Activity

    Learn more →
    GOOGL
    0
    Sells (3M)
    0
    Sells (12M)
    No open market insider sales found.
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
    VRTX
    0
    Sells (3M)
    52
    Sells (12M)
    Total value (12M): $158.10M
    MCKECHNIE DUNCAN J.
    Officer
    $799,779
    @ $519.00 · 2026-07-02
    TATSIS OURANIA
    Officer
    $787,485
    @ $524.99 · 2026-07-02
    LIU JOY
    Officer
    $416,244
    @ $502.71 · 2026-07-01
    BOZIC CARMEN
    Officer
    $287,570
    @ $482.50 · 2026-06-26
    BOZIC CARMEN
    Officer
    $471,413
    @ $462.17 · 2026-06-18
    BOZIC CARMEN
    Officer
    $1.83M
    @ $450.00 · 2026-06-15
    BOZIC CARMEN
    Officer
    $785,250
    @ $450.00 · 2026-06-05
    LIU JOY
    Officer
    $364,245
    @ $439.91 · 2026-06-01
    BOZIC CARMEN
    Officer
    $888,300
    @ $450.00 · 2026-05-29
    BUNNAGE MARK E.
    Officer
    $14,964
    @ $453.45 · 2026-05-15
    BOZIC CARMEN
    Officer
    $613,971
    @ $453.45 · 2026-05-15
    BOZIC CARMEN
    Officer
    $3.14M
    @ $450.00 · 2026-05-12
    BHATIA SANGEETA N
    Director
    $134,746
    @ $423.73 · 2026-05-04
    LIU JOY
    Officer
    $469,222
    @ $425.02 · 2026-05-01
    LIU JOY
    Officer
    $439,288
    @ $449.17 · 2026-04-01
    BOZIC CARMEN
    Officer
    $1.05M
    @ $450.95 · 2026-03-27
    BOZIC CARMEN
    Officer
    $1.12M
    @ $481.79 · 2026-03-13
    MCKECHNIE DUNCAN J.
    Officer
    $1.31M
    @ $498.42 · 2026-03-11
    MCKECHNIE DUNCAN J.
    Officer
    $1.16M
    @ $475.30 · 2026-03-04
    LIU JOY
    Officer
    $442,396
    @ $495.96 · 2026-03-02
    BOZIC CARMEN
    Officer
    $1.12M
    @ $480.31 · 2026-02-27
    KEWALRAMANI RESHMA
    Chief Executive Officer
    $19.74M
    @ $493.47 · 2026-02-27
    AMBROSE KRISTEN
    Officer
    $172,560
    @ $483.36 · 2026-02-26
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $324,882
    @ $486.35 · 2026-02-25
    MCKECHNIE DUNCAN J.
    Officer
    $2.39M
    @ $487.65 · 2026-02-25
    BUNNAGE MARK E.
    Officer
    $301,537
    @ $486.35 · 2026-02-25
    AMBROSE KRISTEN
    Officer
    $108,456
    @ $486.35 · 2026-02-25
    BILLER JONATHAN PRIM
    Officer
    $459,601
    @ $486.35 · 2026-02-25
    TATSIS OURANIA
    Officer
    $126,451
    @ $486.35 · 2026-02-25
    SACHDEV AMIT
    Officer
    $897,802
    @ $486.35 · 2026-02-25
    SACHDEV AMIT
    Officer
    $27.48M
    @ $468.83 · 2026-02-19
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $1.38M
    @ $484.93 · 2026-02-18
    BUNNAGE MARK E.
    Officer
    $1.75M
    @ $484.31 · 2026-02-18
    AMBROSE KRISTEN
    Officer
    $1.06M
    @ $484.87 · 2026-02-18
    BILLER JONATHAN PRIM
    Officer
    $1.80M
    @ $484.18 · 2026-02-18
    TATSIS OURANIA
    Officer
    $472,395
    @ $483.52 · 2026-02-18
    BILLER JONATHAN PRIM
    Officer
    $493,012
    @ $499.00 · 2026-02-13
    TATSIS OURANIA
    Officer
    $749,985
    @ $499.99 · 2026-02-13
    BHATIA SANGEETA N
    Director
    $133,000
    @ $500.00 · 2026-02-13
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $806,213
    @ $460.43 · 2026-02-11
    BUNNAGE MARK E.
    Officer
    $930,529
    @ $460.43 · 2026-02-11
    AMBROSE KRISTEN
    Officer
    $633,552
    @ $460.43 · 2026-02-11
    BILLER JONATHAN PRIM
    Officer
    $886,328
    @ $460.43 · 2026-02-11
    TATSIS OURANIA
    Officer
    $214,560
    @ $460.43 · 2026-02-11
    TATSIS OURANIA
    Officer
    $2.14M
    @ $474.99 · 2026-01-07
    WAGNER CHARLES F JR
    Chief Operating Officer
    $4.39M
    @ $461.00 · 2026-01-06
    TATSIS OURANIA
    Officer
    $2.02M
    @ $449.99 · 2025-12-03
    BILLER JONATHAN PRIM
    Officer
    $155,803
    @ $449.00 · 2025-12-03
    WAGNER CHARLES F JR
    Chief Operating Officer
    $6.38M
    @ $456.00 · 2025-12-03
    LEIDEN JEFFREY M
    Officer and Director
    $28.65M
    @ $449.20 · 2025-12-03
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $1.09M
    @ $434.58 · 2025-11-17
    LEIDEN JEFFREY M
    Officer and Director
    $32.29M
    @ $440.60 · 2025-11-14
    BILLER JONATHAN PRIM
    Officer
    $280,522
    @ $404.21 · 2025-10-02
    BHATIA SANGEETA N
    Director
    $102,860
    @ $386.69 · 2025-08-27
    ALTSHULER DAVID
    Officer
    $22,084
    @ $424.69 · 2025-05-15
    BHATIA SANGEETA N
    Director
    $202,344
    @ $505.86 · 2025-05-02
    ALTSHULER DAVID
    Officer
    $1.65M
    @ $510.00 · 2025-03-13
    ALTSHULER DAVID
    Officer
    $1.62M
    @ $500.00 · 2025-03-10
    TATSIS OURANIA
    Officer
    $1.62M
    @ $499.99 · 2025-03-10
    WAGNER CHARLES F JR
    Chief Financial Officer
    $1.65M
    @ $500.00 · 2025-03-10
    TATSIS OURANIA
    Officer
    $1.97M
    @ $485.49 · 2025-03-04
    ALTSHULER DAVID
    Officer
    $1.58M
    @ $490.00 · 2025-03-03
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $1.26M
    @ $475.34 · 2025-02-27
    ALTSHULER DAVID
    Officer
    $610,560
    @ $480.00 · 2025-02-27
    TATSIS OURANIA
    Officer
    $251,930
    @ $475.34 · 2025-02-27
    ATKINSON EDWARD MORROW III
    Officer
    $849,839
    @ $480.95 · 2025-02-25
    AMBROSE KRISTEN
    Officer
    $425,160
    @ $480.95 · 2025-02-25
    ALTSHULER DAVID
    Officer
    $407,846
    @ $480.95 · 2025-02-25
    TATSIS OURANIA
    Officer
    $170,256
    @ $480.95 · 2025-02-25
    ALTSHULER DAVID
    Officer
    $533,280
    @ $480.00 · 2025-02-20
    AMBROSE KRISTEN
    Officer
    $305,345
    @ $455.06 · 2025-02-18
    TATSIS OURANIA
    Officer
    $111,035
    @ $455.06 · 2025-02-18
    BILLER JONATHAN PRIM
    Officer
    $754,034
    @ $455.06 · 2025-02-18
    ATKINSON EDWARD MORROW III
    Chief Technology Officer
    $803,323
    @ $459.83 · 2025-02-11
    AMBROSE KRISTEN
    Officer
    $632,726
    @ $459.83 · 2025-02-11
    TATSIS OURANIA
    Officer
    $142,547
    @ $459.83 · 2025-02-11
    BILLER JONATHAN PRIM
    Officer
    $1.58M
    @ $459.87 · 2025-02-11
    ALTSHULER DAVID
    Officer
    $7,178
    @ $478.53 · 2024-11-15
    WAGNER CHARLES F JR
    Chief Financial Officer
    $1.55M
    @ $518.27 · 2024-11-11
    KEWALRAMANI RESHMA
    Chief Executive Officer
    $7.83M
    @ $515.00 · 2024-11-08
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

    🎭 Mr. Market's Mood

    Learn more →
    GOOGL
    FearGreed
    😨Fear(23/100)

    "Market is pessimistic — investigate whether fears are temporary or structural"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
    VRTX
    FearGreed
    😏Greed(71/100)

    "Market is optimistic — be cautious and ensure you have a margin of safety"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    ⚖️ Buffett Signal

    Learn more →
    GOOGL
    ⚪Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Fear (23)
    VRTX
    ⚪Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Greed (71)
    View GOOGL Full AnalysisView VRTX Full Analysis

    Frequently Asked Questions: GOOGL vs VRTX

    Is Alphabet Inc. or Vertex Pharmaceuticals Incorporated more undervalued in 2026?▼

    Based on our discounted cash flow model, VRTX trades at a -47.1% margin of safety (intrinsic value $380 vs. price $559), compared to GOOGL's -3447.8% margin of safety (intrinsic $8 vs. $280).

    Which stock has a wider economic moat, Alphabet Inc. or Vertex Pharmaceuticals Incorporated?▼

    GOOGL scores 89/100 (Wide moat), while VRTX scores 65/100 (Narrow moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

    Is Alphabet Inc. in financial distress?▼

    GOOGL's Altman Z-Score of 2.4 places it in the Grey zone, signaling elevated bankruptcy risk. VRTX scores 12.0 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

    Which company has better free cash flow, Alphabet Inc. or Vertex Pharmaceuticals Incorporated?▼

    Vertex Pharmaceuticals Incorporated (VRTX) generates a 1.9% free cash flow yield, compared to Alphabet Inc.'s -0.0%. A higher FCF yield means the business converts more of its market value into cash that can be returned to shareholders or reinvested.

    Which stock has higher return on invested capital, Alphabet Inc. or Vertex Pharmaceuticals Incorporated?▼

    VRTX earns 17.0% ROIC versus GOOGL's 14.3%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

    GOOGL vs VRTX: Which Is the Better Buy in 2026? | SafetyMargin.io