Compare StocksGILD vs PFE

Gilead Sciences, Inc. (GILD) vs Pfizer Inc. (PFE)

GILD
Gilead Sciences, Inc.
$141.11
VS
PFE
Pfizer Inc.
$27.41

Rewards

GILD
  • Gilead Sciences, Inc. has maintained ROIC above 10% for 4 consecutive years, suggesting solid business economics.
  • Gross margin of 78.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Gilead Sciences, Inc. scores 92/100 on the Economic Moat Score (Wide Moat), with margin stability as the strongest competitive dimension.
PFE
  • Gross margin of 75.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Dividend yield of 6.28% with a consistent or growing payout over the past 4 years.
  • FCF yield of 8.6% is historically attractive — the business generates significant cash relative to its price.

Risks

GILD
  • 12 insider sales totaling $44.1M with no purchases in the past 3 months — insiders are reducing their exposure.
PFE
  • ROIC has declined by 13.9 percentage points over the observed period, which may signal competitive erosion.
  • Free cash flow has declined at a 29.6% CAGR over the past 4 years — a concerning trend.

Key Valuation Metrics

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GILD
PFE
Valuation
$7.54B
Free Cash Flow
$13.43B
4.30%
FCF Yield
8.61%
20.84
Trailing P/E
20.15
14.68
Forward P/E
9.69
Quality & Moat
18.05%
ROIC
7.67%
37.62%
ROE
8.96%
78.84%
Gross Margin
75.81%
0.89
PEG Ratio
N/A
Balance Sheet Safety
1.13
Debt / Equity
0.78
N/A
Interest Coverage
N/A
1.09
Net Debt / EBITDA
2.10
2.32%
Dividend Yield
6.28%
GILD: 3Ties: 3PFE: 5
GILDPFE

Historical Fundamentals

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GILD

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

$1 Retained Earnings Test

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GILD
$15.46
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$2.92B
Δ Market Cap
+$45.23B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-146.18B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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GILD
13.4% Margin of Safety
Price is 13.4% below estimated fair value
Current Price: $141.11
Fair Value: $162.98
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
PFE
140.2% Overvalued
Price is 140.2% above estimated fair value
Current Price: $27.41
Fair Value: $11.41
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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GILD

What growth rate is the market pricing in at $141?

+9.3%
Market-Implied Owner Earnings Growth
Standard FCF implies +10.9%

The market implies +9.3% Owner Earnings growth, below historical trends — potential opportunity.

Standard FCF implies a more demanding +10.9%, reflecting heavy growth investment expected to generate future returns.

PFE

What growth rate is the market pricing in at $27?

+11.8%
Market-Implied Owner Earnings Growth
Standard FCF implies +4.3%

The market implies +11.8% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +4.3%, reflecting heavy growth investment.

Economic Moat Score

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GILD
92/100
Wide Moat
70+ Wide · 40-69 Narrow · <40 None

Wide moat with strength across all dimensions. Margin Stability is the standout factor.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

Forensic Accounting

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GILD
-2.46
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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GILD
Insiders 0.1%Institutions 92.6%Retail & Other 7.3%
No. of Institutional Holders2,969
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
PFE
Insiders 0.1%Institutions 67.7%Retail & Other 32.2%
No. of Institutional Holders3,693
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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GILD
0
Buys (3M)
0
Buys (12M)
No open market insider purchases found.
Open market purchases · includes direct & indirect ownership · excludes option exercises
PFE
0
Buys (3M)
0
Buys (12M)
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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GILD
12
Sells (3M)
40
Sells (12M)
Total value (12M): $74.81M
MERCIER JOHANNA
Officer
$432,690
@ $144.23 · 2026-03-16
DICKINSON ANDREW D
Chief Financial Officer
$432,690
@ $144.23 · 2026-03-16
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.45M
@ $144.79 · 2026-02-27
MERCIER JOHANNA
Officer
$4.32M
@ $154.44 · 2026-02-17
DICKINSON ANDREW D
Chief Financial Officer
$463,290
@ $154.43 · 2026-02-17
O'DAY DANIEL PATRICK
Chief Executive Officer
$17.35M
@ $150.00 · 2026-02-05
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.40M
@ $139.89 · 2026-01-28
O'DAY DANIEL PATRICK
Chief Executive Officer
$15.61M
@ $135.00 · 2026-01-23
BLUESTONE JEFFREY
Director
$617,500
@ $123.50 · 2026-01-20
MERCIER JOHANNA
Officer
$372,930
@ $124.31 · 2026-01-15
DICKINSON ANDREW D
Chief Financial Officer
$372,930
@ $124.31 · 2026-01-15
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.25M
@ $124.83 · 2025-12-29
MERCIER JOHANNA
Officer
$366,000
@ $122.00 · 2025-12-15
DICKINSON ANDREW D
Chief Financial Officer
$366,000
@ $122.00 · 2025-12-15
KRAMER KELLY A
Director
$713,186
@ $127.10 · 2025-11-28
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.27M
@ $126.54 · 2025-11-28
BLUESTONE JEFFREY
Director
$625,400
@ $125.08 · 2025-11-28
MERCIER JOHANNA
Officer
$3.52M
@ $125.86 · 2025-11-17
DICKINSON ANDREW D
Chief Financial Officer
$313,075
@ $125.23 · 2025-11-17
TELMAN DEBORAH H
General Counsel
$6.59M
@ $122.85 · 2025-11-12
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.19M
@ $119.39 · 2025-10-28
MERCIER JOHANNA
Officer
$354,240
@ $118.08 · 2025-10-15
DICKINSON ANDREW D
Chief Financial Officer
$295,200
@ $118.08 · 2025-10-15
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.12M
@ $111.66 · 2025-09-29
MERCIER JOHANNA
Officer
$340,710
@ $113.57 · 2025-09-15
DICKINSON ANDREW D
Chief Financial Officer
$283,925
@ $113.57 · 2025-09-15
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.14M
@ $113.63 · 2025-08-28
MERCIER JOHANNA
Officer
$3.32M
@ $118.53 · 2025-08-15
DICKINSON ANDREW D
Chief Financial Officer
$296,325
@ $118.53 · 2025-08-15
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.14M
@ $113.94 · 2025-07-28
MERCIER JOHANNA
Officer
$333,090
@ $111.03 · 2025-07-15
DICKINSON ANDREW D
Chief Financial Officer
$277,575
@ $111.03 · 2025-07-15
BLUESTONE JEFFREY
Director
$548,700
@ $109.74 · 2025-07-14
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.10M
@ $110.45 · 2025-06-30
MERCIER JOHANNA
Officer
$330,510
@ $110.17 · 2025-06-16
DICKINSON ANDREW D
Chief Financial Officer
$275,425
@ $110.17 · 2025-06-16
O'DAY DANIEL PATRICK
Chief Executive Officer
$1.10M
@ $110.42 · 2025-05-30
MERCIER JOHANNA
Officer
$3.01M
@ $107.52 · 2025-05-22
DICKINSON ANDREW D
Chief Financial Officer
$249,550
@ $99.82 · 2025-05-15
DICKINSON ANDREW D
Chief Financial Officer
$266,000
@ $106.40 · 2025-04-15
DICKINSON ANDREW D
Chief Financial Officer
$276,325
@ $110.53 · 2025-03-17
DICKINSON ANDREW D
Chief Financial Officer
$2.12M
@ $118.17 · 2025-03-10
DICKINSON ANDREW D
Chief Financial Officer
$260,225
@ $104.09 · 2025-02-18
DICKINSON ANDREW D
Chief Financial Officer
$14.07M
@ $102.22 · 2025-02-12
DICKINSON ANDREW D
Chief Financial Officer
$13.82M
@ $97.22 · 2025-01-31
DICKINSON ANDREW D
Chief Financial Officer
$228,375
@ $91.35 · 2025-01-15
DICKINSON ANDREW D
Chief Financial Officer
$781,660
@ $91.96 · 2024-12-16
DICKINSON ANDREW D
Chief Financial Officer
$23.07M
@ $92.76 · 2024-11-29
PARSEY MERDAD V
Officer
$15.09M
@ $91.92 · 2024-11-27
BLUESTONE JEFFREY
Director
$620,356
@ $91.39 · 2024-11-26
PARSEY MERDAD V
Officer
$2.34M
@ $91.50 · 2024-11-06
MERCIER JOHANNA
Officer
$456,400
@ $91.28 · 2024-11-06
PARSEY MERDAD V
Officer
$167,660
@ $83.83 · 2024-10-01
PARSEY MERDAD V
Officer
$1.80M
@ $84.50 · 2024-09-12
MERCIER JOHANNA
Officer
$2.46M
@ $83.78 · 2024-09-12
MERCIER JOHANNA
Officer
$742,299
@ $78.03 · 2024-08-28
MERCIER JOHANNA
Officer
$406,150
@ $73.98 · 2024-08-13
PARSEY MERDAD V
Officer
$137,260
@ $68.63 · 2024-07-01
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
PFE
0
Sells (3M)
0
Sells (12M)
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
DAMICO JENNIFER B.
Officer
$147,714
@ $28.66 · 2024-08-13
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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GILD
FearGreed
😐Neutral(55/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
PFE
FearGreed
😏Greed(64/100)

"Market is optimistic — be cautious and ensure you have a margin of safety"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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GILD
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (55)
PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Greed (64)
View GILD Full AnalysisView PFE Full Analysis
Gilead Sciences, Inc. (GILD) vs Pfizer Inc. (PFE) Stock Comparison | SafetyMargin.io