Compare StocksDGX vs PFE

Quest Diagnostics Incorporated (DGX) vs Pfizer Inc. (PFE): Which Is the Better Buy in 2026?

As of 2026-09-17, DGX is overvalued at $247, with a DCF intrinsic value of $149 and a margin of safety of -66%. PFE is overvalued at $27, with an intrinsic value of $22 and a margin of safety of -22%. Of the two, PFE has the wider margin of safety.

DGX
Quest Diagnostics Incorporated
$247.08
VS
PFE
Pfizer Inc.
$27.46

Rewards

DGX
    PFE
    • Gross margin of 74.7% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
    • Insiders have bought $3.0M worth of stock in the past 3 months — significant skin in the game.

    Risks

    DGX
    • Each dollar of retained earnings has produced only $0.36 of earning power — shareholders may have been better served by dividends.
    • Trailing P/E of 26.3x is 37% above the historical average of 19.1x — the stock trades at a premium to its own history.
    PFE
    • ROIC has declined by 15.9 percentage points over the past 4 years, which may signal competitive erosion.
    • FCF yield of 8.0% suggests reasonable valuation assuming continued moderate growth.
    • PEG ratio of 12.68 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.

    Key Valuation Metrics

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    DGX
    PFE
    Valuation
    $1.36B
    Free Cash Flow
    $12.49B
    4.98%
    FCF Yield
    7.98%
    26.26
    Trailing P/E
    36.13
    20.49
    Forward P/E
    9.48
    Quality & Moat
    9.74%
    ROIC
    9.42%
    14.60%
    ROE
    5.01%
    33.19%
    Gross Margin
    74.72%
    1.84
    PEG Ratio
    12.68
    Balance Sheet Safety
    0.73
    Net Debt / Equity
    0.61
    N/A
    Interest Coverage
    N/A
    2.55
    Net Debt / EBITDA
    2.04
    1.39%
    Dividend Yield
    6.26%
    DGX: 3Ties: 2PFE: 7
    DGXPFE

    Historical Fundamentals

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    DGX

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    PFE

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

    $1 Retained Earnings Test

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    DGX
    $1.03
    created per $1 retained over 3 years
    Value Creator
    Σ Retained
    $1.72B
    Δ Market Cap
    +$1.77B
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
    PFE
    N/A
    Net losses over 3 years — test not applicable
    Company had negative cumulative retained earnings
    Σ Retained
    $-10.61B
    Δ Market Cap
    $-146.18B
    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
    > $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

    Discounted Cash Flow (DCF) Analysis

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    DGX
    65.8% Overvalued
    Price is 65.8% above estimated fair value
    Current Price: $247.08
    Fair Value: $149.06
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued
    PFE
    22.4% Overvalued
    Price is 22.4% above estimated fair value
    Current Price: $27.46
    Fair Value: $22.43
    Strongly undervalued
    Undervalued
    Fairly valued
    Overvalued
    Strongly overvalued

    Reverse DCF — Market-Implied Growth

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    DGX

    What growth rate is the market pricing in at $247?

    +14.1%
    Market-Implied Owner Earnings Growth
    Standard FCF implies +10.4%

    The market implies +14.1% Owner Earnings growth, above historical trends.

    Standard FCF implies a demanding +10.4%, reflecting heavy growth investment.

    PFE

    What growth rate is the market pricing in at $27?

    +6.1%
    Market-Implied Owner Earnings Growth
    Standard FCF implies +5.2%

    The market implies +6.1% Owner Earnings growth, above historical trends.

    Standard FCF implies a demanding +5.2%, reflecting heavy growth investment.

    Economic Moat Score

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    DGX
    56/100
    Narrow Moat
    70+ Wide · 40-69 Narrow · <40 None

    Narrow moat with margin stability as the key competitive advantage. Improving roic consistency would strengthen the moat.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
    PFE
    35/100
    No Moat
    70+ Wide · 40-69 Narrow · <40 None

    No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

    Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

    Forensic Accounting

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    DGX
    -2.66
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
    PFE
    -2.53
    Unlikely Manipulator
    Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

    M-Score Trend

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

    Ownership Breakdown

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    DGX
    Insiders 0.4%Institutions 99.0%Retail & Other 0.5%
    No. of Institutional Holders1,524
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
    PFE
    Insiders 0.1%Institutions 69.1%Retail & Other 30.8%
    No. of Institutional Holders3,645
    High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

    High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

    Insider Buying Activity

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    DGX
    6
    Buys (3M)
    15
    Buys (12M)
    Total value (12M): $77,930
    MAIN TIMOTHY L
    Director
    $4,343
    @ $206.81 · 2026-07-22
    CARTER ROBERT B
    Director
    $2,275
    @ $206.82 · 2026-07-22
    PLEWMAN PATRICK
    Officer
    $9,513
    @ $206.80 · 2026-07-22
    LASSITER WRIGHT III
    Director
    $1,241
    @ $206.83 · 2026-07-22
    KUPPUSAMY KARTHIK
    Officer
    $7,652
    @ $206.81 · 2026-07-22
    DELANEY MARK E
    Officer
    $7,031
    @ $206.79 · 2026-07-22
    PLEWMAN PATRICK
    Officer
    $9,540
    @ $194.69 · 2026-04-20
    LASSITER WRIGHT III
    Director
    $1,168
    @ $194.67 · 2026-04-20
    KUPPUSAMY KARTHIK
    Officer
    $7,593
    @ $194.69 · 2026-04-20
    DELANEY MARK E
    Officer
    $7,204
    @ $194.70 · 2026-04-20
    CARTER ROBERT B
    Director
    $1,101
    @ $183.50 · 2026-01-28
    GREGG VICKY B
    Director
    $12,295
    @ $183.51 · 2026-01-28
    LASSITER WRIGHT III
    Director
    $1,285
    @ $183.57 · 2026-01-28
    KUPPUSAMY KARTHIK
    Officer
    $2,936
    @ $183.50 · 2026-01-28
    DELANEY MARK E
    Officer
    $2,753
    @ $183.53 · 2026-01-28
    GREGG VICKY B
    Director
    $13,232
    @ $167.49 · 2025-07-21
    SAMAD SAMER ABDUL
    Chief Financial Officer
    $12,060
    @ $167.50 · 2025-07-21
    LASSITER WRIGHT III
    Director
    $1,173
    @ $167.57 · 2025-07-21
    KUPPUSAMY KARTHIK
    Officer
    $4,522
    @ $167.48 · 2025-07-21
    DELANEY MARK E
    Officer
    $2,847
    @ $167.47 · 2025-07-21
    PLEWMAN PATRICK
    Officer
    $13,318
    @ $164.42 · 2025-04-21
    SAMAD SAMER ABDUL
    Chief Financial Officer
    $12,167
    @ $164.42 · 2025-04-21
    KUPPUSAMY KARTHIK
    Officer
    $4,439
    @ $164.41 · 2025-04-21
    DELANEY MARK E
    Officer
    $4,111
    @ $164.44 · 2025-04-21
    PLEWMAN PATRICK
    Officer
    $9,008
    @ $158.04 · 2025-01-29
    GREGG VICKY B
    Director
    $11,379
    @ $158.04 · 2025-01-29
    SAMAD SAMER ABDUL
    Chief Financial Officer
    $5,531
    @ $158.03 · 2025-01-29
    KUPPUSAMY KARTHIK
    Officer
    $1,896
    @ $158.00 · 2025-01-29
    DELANEY MARK E
    Officer
    $632.00
    @ $158.00 · 2025-01-29
    Open market purchases · includes direct & indirect ownership · excludes option exercises
    PFE
    3
    Buys (3M)
    3
    Buys (12M)
    Total value (12M): $2.96M
    BOURLA ALBERT
    Chief Executive Officer
    $1.00M
    @ $26.34 · 2026-08-12
    BLAYLOCK RONALD E
    Director
    $998,821
    @ $25.46 · 2026-08-05
    BUCKLEY MORTIMER J.
    Director
    $960,369
    @ $25.52 · 2026-08-05
    BLAYLOCK RONALD E
    Director
    $499,072
    @ $25.65 · 2025-02-13
    GOTTLIEB SCOTT
    Director
    $28,240
    @ $28.24 · 2024-10-30
    Open market purchases · includes direct & indirect ownership · excludes option exercises

    Open market purchases · includes direct & indirect ownership · excludes option exercises.

    Insider Selling Activity

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    DGX
    3
    Sells (3M)
    22
    Sells (12M)
    Total value (12M): $38.57M
    DAVIS JAMES E
    Chief Executive Officer
    $2.43M
    @ $242.72 · 2026-09-01
    PREVOZNIK MICHAEL E
    General Counsel
    $5.51M
    @ $243.11 · 2026-08-28
    DELANEY MARK E
    Officer
    $376,288
    @ $235.18 · 2026-07-28
    KUPPUSAMY KARTHIK
    Officer
    $1.63M
    @ $200.00 · 2026-06-04
    PREVOZNIK MICHAEL E
    General Counsel
    $799,682
    @ $206.21 · 2026-03-05
    DOHERTY CATHERINE T
    Officer
    $1.15M
    @ $206.21 · 2026-03-05
    PLEWMAN PATRICK
    Officer
    $588,730
    @ $206.21 · 2026-03-05
    KUPPUSAMY KARTHIK
    Officer
    $538,372
    @ $204.86 · 2026-03-04
    PREVOZNIK MICHAEL E
    General Counsel
    $109,266
    @ $207.73 · 2026-03-03
    DOHERTY CATHERINE T
    Officer
    $131,285
    @ $207.73 · 2026-03-03
    PLEWMAN PATRICK
    Officer
    $85,169
    @ $207.73 · 2026-03-03
    PREVOZNIK MICHAEL E
    General Counsel
    $227,566
    @ $204.83 · 2026-02-19
    DOHERTY CATHERINE T
    Officer
    $293,521
    @ $204.83 · 2026-02-19
    PLEWMAN PATRICK
    Officer
    $196,227
    @ $204.83 · 2026-02-19
    DOHERTY CATHERINE T
    Officer
    $5.39M
    @ $206.15 · 2026-02-13
    PLEWMAN PATRICK
    Officer
    $1.16M
    @ $204.00 · 2026-02-10
    DAVIS J E CAUSEY
    Chief Executive Officer
    $10.59M
    @ $192.22 · 2025-11-25
    GREGG VICKY B
    Director
    $239,700
    @ $191.76 · 2025-11-25
    DELANEY MARK E
    Officer
    $1.49M
    @ $187.35 · 2025-11-18
    PFEIFFER GARY M
    Director
    $270,317
    @ $182.40 · 2025-10-22
    PREVOZNIK MICHAEL E
    General Counsel
    $42,706
    @ $188.13 · 2025-09-26
    PREVOZNIK MICHAEL E
    General Counsel
    $5.33M
    @ $187.12 · 2025-09-24
    PLEWMAN PATRICK
    Officer
    $365,375
    @ $185.00 · 2025-08-21
    PLEWMAN PATRICK
    Officer
    $829,356
    @ $183.00 · 2025-08-19
    PLEWMAN PATRICK
    Officer
    $355,500
    @ $180.00 · 2025-08-15
    PLEWMAN PATRICK
    Officer
    $968,625
    @ $175.00 · 2025-08-06
    KUPPUSAMY KARTHIK
    Officer
    $1.76M
    @ $167.95 · 2025-07-31
    DELANEY MARK E
    Officer
    $306,800
    @ $175.51 · 2025-05-13
    DAVIS JAMES E
    Chief Executive Officer
    $6.60M
    @ $168.46 · 2025-04-02
    KUPPUSAMY KARTHIK
    Officer
    $434,350
    @ $170.00 · 2025-04-02
    PREVOZNIK MICHAEL E
    General Counsel
    $789,310
    @ $170.00 · 2025-03-17
    DOHERTY CATHERINE T
    Officer
    $935,078
    @ $174.13 · 2025-03-05
    PREVOZNIK MICHAEL E
    General Counsel
    $104,068
    @ $175.79 · 2025-03-04
    DOHERTY CATHERINE T
    Officer
    $125,866
    @ $175.79 · 2025-03-04
    PREVOZNIK MICHAEL E
    General Counsel
    $91,138
    @ $172.61 · 2025-02-27
    DOHERTY CATHERINE T
    Officer
    $142,231
    @ $172.61 · 2025-02-27
    PREVOZNIK MICHAEL E
    General Counsel
    $103,278
    @ $170.99 · 2025-02-20
    DOHERTY CATHERINE T
    Officer
    $244,515
    @ $170.51 · 2025-02-20
    PLEWMAN PATRICK
    Officer
    $54,307
    @ $169.71 · 2025-02-19
    GREGG VICKY B
    Director
    $205,710
    @ $164.57 · 2025-02-05
    DELANEY MARK E
    Officer
    $66,214
    @ $164.30 · 2025-02-05
    PREVOZNIK MICHAEL E
    General Counsel
    $5.73M
    @ $163.07 · 2024-11-29
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
    PFE
    1
    Sells (3M)
    2
    Sells (12M)
    Total value (12M): $134,661
    DAMICO JENNIFER B.
    Officer
    $83,261
    @ $25.40 · 2026-08-05
    DAMICO JENNIFER B.
    Officer
    $51,400
    @ $25.70 · 2026-06-09
    DAMICO JENNIFER B.
    Officer
    $64,825
    @ $25.93 · 2025-03-04
    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

    Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

    🎭 Mr. Market's Mood

    Learn more →
    DGX
    FearGreed
    😏Greed(67/100)

    "Market is optimistic — be cautious and ensure you have a margin of safety"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
    PFE
    FearGreed
    😐Neutral(56/100)

    "Market is pricing this stock without strong emotion in either direction"

    Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

    ⚖️ Buffett Signal

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    DGX
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Greed (67)
    PFE
    Awaiting DCF Data

    The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

    DCF Margin of Safety: N/AMr. Market's Mood: Neutral (56)
    View DGX Full AnalysisView PFE Full Analysis

    Frequently Asked Questions: DGX vs PFE

    Is Quest Diagnostics Incorporated or Pfizer Inc. more undervalued in 2026?

    Based on our discounted cash flow model, PFE trades at a -22.4% margin of safety (intrinsic value $22 vs. price $27), compared to DGX's -65.8% margin of safety (intrinsic $149 vs. $247).

    Which stock has a wider economic moat, Quest Diagnostics Incorporated or Pfizer Inc.?

    DGX scores 56/100 (Narrow moat), while PFE scores 35/100 (None moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

    Is Pfizer Inc. in financial distress?

    PFE's Altman Z-Score of 2.1 places it in the Grey zone, signaling elevated bankruptcy risk. DGX scores 3.1 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

    Which company has better free cash flow, Quest Diagnostics Incorporated or Pfizer Inc.?

    Pfizer Inc. (PFE) generates a 8.0% free cash flow yield, compared to Quest Diagnostics Incorporated's 5.0%. A higher FCF yield means the business converts more of its market value into cash that can be returned to shareholders or reinvested.

    Which stock has higher return on invested capital, Quest Diagnostics Incorporated or Pfizer Inc.?

    DGX earns 9.7% ROIC versus PFE's 9.4%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

    Which dividend is safer, Quest Diagnostics Incorporated's or Pfizer Inc.'s?

    DGX's dividend earns a safety score of 94/100 (Very Safe), compared to PFE's 24/100 (Unsafe). DGX has raised its dividend for 3 consecutive years.

    DGX vs PFE: Which Is the Better Buy in 2026? | SafetyMargin.io