Compare StocksCBOE vs PFE

Cboe Global Markets, Inc. (CBOE) vs Pfizer, Inc. (PFE): Which Is the Better Buy in 2026?

As of 2026-08-03, CBOE is overvalued at $310, with a DCF intrinsic value of $232 and a margin of safety of -34%. PFE is undervalued at $25, with an intrinsic value of $127985960274 and a margin of safety of 100%. Of the two, PFE has the wider margin of safety.

CBOE
Cboe Global Markets, Inc.
$310.23
VS
PFE
Pfizer, Inc.
$25.01

Rewards

CBOE
  • Cboe Global Markets, Inc. scores 80/100 on the Economic Moat Score (Wide Moat), with reinvestment efficiency as the strongest competitive dimension.
  • Free cash flow has grown at a 41.7% CAGR over the past 4 years, demonstrating strong earnings power growth.
  • Each dollar of retained earnings has created $4.81 of earning power — management is an exceptional capital allocator.
PFE
  • Gross margin of 74.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Trailing P/E of 19.1x is 37% below the historical average of 30.4x — potentially undervalued relative to its own history.

Risks

CBOE
  • FCF yield of 5.2% suggests reasonable valuation assuming continued moderate growth.
  • PEG ratio of 2.93 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
PFE
  • ROIC has declined by 15.9 percentage points over the past 4 years, which may signal competitive erosion.
  • PEG ratio of 2.94 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
  • Altman Z-Score of 1.38 places the company in the distress zone — financial patterns resemble those of companies that experienced bankruptcy.

Key Valuation Metrics

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CBOE
PFE
Valuation
$1.68B
Free Cash Flow
$12.38B
5.18%
FCF Yield
N/A
24.16
Trailing P/E
19.09
20.45
Forward P/E
8.85
Quality & Moat
19.22%
ROIC
10.19%
26.30%
ROE
8.31%
54.08%
Gross Margin
74.80%
2.93
PEG Ratio
2.94
Balance Sheet Safety
Net cash
Net Debt / Equity
0.57
N/A
Interest Coverage
N/A
-0.40
Net Debt / EBITDA
2.03
0.93%
Dividend Yield
6.88%
CBOE: 4Ties: 2PFE: 5
CBOEPFE

Historical Fundamentals

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CBOE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation. The dashed forward point is the forward P/E — today's price ÷ analyst consensus EPS.

$1 Retained Earnings Test

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CBOE
$6.94
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$1.87B
Δ Market Cap
+$12.97B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-26.34
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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CBOE
34.0% Overvalued
Price is 34.0% above estimated fair value
Current Price: $310.23
Fair Value: $231.54
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
PFE
100.0% Margin of Safety
Price is 100.0% below estimated fair value
Current Price: $25.01
Fair Value: $127985960274.09
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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CBOE

What growth rate is the market pricing in at $310?

+12.1%
Market-Implied Owner Earnings Growth
Standard FCF implies +6.9%

The market implies +12.1% Owner Earnings growth, below historical trends — potential opportunity.

Standard FCF implies a more demanding +6.9%, reflecting heavy growth investment expected to generate future returns.

PFE

What growth rate is the market pricing in at $25?

-14.2%
Market-Implied Owner Earnings Growth
Standard FCF implies -15.0%

The market implies -14.2% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding -15.0%, reflecting heavy growth investment.

Economic Moat Score

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CBOE
80/100
Wide Moat
70+ Wide · 40-69 Narrow · <40 None

Wide moat with strength across all dimensions. Reinvestment Efficiency is the standout factor.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

Forensic Accounting

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CBOE
-2.91
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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CBOE
Insiders 0.3%Institutions 92.2%Retail & Other 7.5%
No. of Institutional Holders1,413
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
PFE
Insiders 0.1%Institutions 69.5%Retail & Other 30.4%
No. of Institutional Holders3,661
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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CBOE
0
Buys (3M)
0
Buys (12M)
No open market insider purchases found.
Open market purchases · includes direct & indirect ownership · excludes option exercises
PFE
0
Buys (3M)
0
Buys (12M)
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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CBOE
1
Sells (3M)
5
Sells (12M)
Total value (12M): $3.25M
FROETSCHER JANET P
Director
$437,944
@ $358.09 · 2026-05-18
WILKINSON ALLEN
Officer
$72,612
@ $292.79 · 2026-02-23
MATTURRI ALEXANDER J. JR.
Director
$428,040
@ $285.36 · 2026-02-18
FITZPATRICK EDWARD J
Director
$1.13M
@ $285.87 · 2026-02-18
ISAACSON CHRISTOPHER A
Chief Operating Officer
$1.18M
@ $236.66 · 2025-09-02
ISAACSON CHRISTOPHER A
Chief Operating Officer
$1.11M
@ $221.37 · 2025-06-09
CLAY CATHERINE R
Officer
$815,235
@ $226.58 · 2025-05-23
GOODMAN JILL R
Director
$560,593
@ $208.86 · 2025-03-13
WILKINSON ALLEN
Officer
$48,135
@ $211.12 · 2025-02-24
HOWSON DAVID
Officer
$1.18M
@ $208.65 · 2025-02-20
INZIRILLO ADAM
Officer
$41,934
@ $209.67 · 2025-02-20
HOWSON DAVID
Officer
$2.27M
@ $206.01 · 2025-02-12
CLAY CATHERINE R
Officer
$635,550
@ $211.85 · 2025-02-10
INZIRILLO ADAM
Officer
$16,933
@ $211.66 · 2025-02-10
INZIRILLO ADAM
Officer
$5,011
@ $200.44 · 2024-12-13
GRIEBENOW JILL
Chief Financial Officer
$346,021
@ $213.33 · 2024-09-04
ISAACSON CHRISTOPHER A
Chief Operating Officer
$1.23M
@ $204.89 · 2024-09-03
WILKINSON ALLEN
Officer
$15,798
@ $213.49 · 2024-08-26
MCPEEK JENNIFER J
Director
$412,220
@ $206.11 · 2024-08-22
CLAY CATHERINE R
Officer
$121,937
@ $203.23 · 2024-08-07
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
PFE
1
Sells (3M)
1
Sells (12M)
Total value (12M): $51,400
DAMICO JENNIFER B.
Officer
$51,400
@ $25.70 · 2026-06-09
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
DAMICO JENNIFER B.
Officer
$147,714
@ $28.66 · 2024-08-13
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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CBOE
FearGreed
😐Neutral(56/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
PFE
FearGreed
😐Neutral(52/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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CBOE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (56)
PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (52)
View CBOE Full AnalysisView PFE Full Analysis

Frequently Asked Questions: CBOE vs PFE

Is Cboe Global Markets, Inc. or Pfizer, Inc. more undervalued in 2026?

Based on our discounted cash flow model, PFE trades at a 100.0% margin of safety (intrinsic value $127985960274 vs. price $25), compared to CBOE's -34.0% margin of safety (intrinsic $232 vs. $310).

Which stock has a wider economic moat, Cboe Global Markets, Inc. or Pfizer, Inc.?

CBOE scores 80/100 (Wide moat), while PFE scores 35/100 (None moat). The moat score measures competitive advantage durability across ROIC consistency, margin stability, revenue predictability, and reinvestment efficiency.

Is Pfizer, Inc. in financial distress?

PFE's Altman Z-Score of 1.4 places it in the Distress zone, signaling elevated bankruptcy risk. CBOE scores 5.6 (Safe zone). The Altman Z-Score is a five-factor model that predicts insolvency within two years; scores below 1.81 indicate significant distress.

Which stock has higher return on invested capital, Cboe Global Markets, Inc. or Pfizer, Inc.?

CBOE earns 19.2% ROIC versus PFE's 10.2%. A higher ROIC means the company generates more profit per dollar of capital employed, a hallmark of durable competitive advantage in Buffett-style analysis.

Which dividend is safer, Cboe Global Markets, Inc.'s or Pfizer, Inc.'s?

CBOE's dividend earns a safety score of 94/100 (Very Safe), compared to PFE's 24/100 (Unsafe). CBOE has raised its dividend for 3 consecutive years.

CBOE vs PFE: Which Is the Better Buy in 2026? | SafetyMargin.io