Compare StocksAMGN vs PFE

Amgen Inc. (AMGN) vs Pfizer Inc. (PFE)

AMGN
Amgen Inc.
$329.82
VS
PFE
Pfizer Inc.
$26.33

Rewards

AMGN
  • Gross margin of 71.4% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Return on equity has consistently exceeded 20% over 4 years, indicating efficient use of shareholder capital.
  • Each dollar of retained earnings has created $3.21 of earning power — management is an exceptional capital allocator.
PFE
  • Gross margin of 75.8% indicates strong pricing power — typical of businesses with significant intellectual property or brand strength.
  • Dividend yield of 6.53% with a consistent or growing payout over the past 4 years.
  • FCF yield of 9.0% is historically attractive — the business generates significant cash relative to its price.

Risks

AMGN
  • ROIC has declined by 6.4 percentage points over the observed period, which may signal competitive erosion.
  • PEG ratio of 5.21 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
  • High leverage (6.24x debt/equity) combined with thin interest coverage (-1.0x) poses financial risk.
PFE
  • ROIC has declined by 13.9 percentage points over the observed period, which may signal competitive erosion.
  • PEG ratio of 13.77 indicates the stock is expensive relative to its expected growth — the market may be pricing in more growth than analysts project.
  • Free cash flow has declined at a 29.6% CAGR over the past 4 years — a concerning trend.

Key Valuation Metrics

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AMGN
PFE
Valuation
$7.44B
Free Cash Flow
$13.43B
4.18%
FCF Yield
8.97%
22.94
Trailing P/E
19.36
14.03
Forward P/E
9.36
Quality & Moat
14.94%
ROIC
7.67%
83.91%
ROE
8.96%
71.44%
Gross Margin
75.81%
5.21
PEG Ratio
13.77
Balance Sheet Safety
6.24
Debt / Equity
0.78
N/A
Interest Coverage
N/A
2.68
Net Debt / EBITDA
2.10
3.06%
Dividend Yield
6.53%
AMGN: 3Ties: 1PFE: 8
AMGNPFE

Historical Fundamentals

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AMGN

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

PFE

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

Price ÷ Earnings Per Share — how many years of current earnings you're paying for at today's price. Lower P/E may indicate undervaluation.

$1 Retained Earnings Test

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AMGN
$9.01
created per $1 retained over 3 years
Exceptional Value Creator
Σ Retained
$4.01B
Δ Market Cap
+$36.10B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer
PFE
N/A
Net losses over 3 years — test not applicable
Company had negative cumulative retained earnings
Σ Retained
$-10.61B
Δ Market Cap
$-146.18B
Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Buffett's "$1 Test": For every $1 of earnings retained, has management created at least $1 of market value?
> $1 created per $1 retained = Value Creator · < $1 created = Value Destroyer

Discounted Cash Flow (DCF) Analysis

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AMGN
87.0% Overvalued
Price is 87.0% above estimated fair value
Current Price: $329.82
Fair Value: $176.36
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued
PFE
130.7% Overvalued
Price is 130.7% above estimated fair value
Current Price: $26.33
Fair Value: $11.41
Strongly undervalued
Undervalued
Fairly valued
Overvalued
Strongly overvalued

Reverse DCF — Market-Implied Growth

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AMGN

What growth rate is the market pricing in at $330?

+12.7%
Market-Implied Owner Earnings Growth
Standard FCF implies +13.2%

The market implies +12.7% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +13.2%, reflecting heavy growth investment.

PFE

What growth rate is the market pricing in at $26?

+11.4%
Market-Implied Owner Earnings Growth
Standard FCF implies +4.0%

The market implies +11.4% Owner Earnings growth, above historical trends.

Standard FCF implies a demanding +4.0%, reflecting heavy growth investment.

Economic Moat Score

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AMGN
54/100
Narrow Moat
70+ Wide · 40-69 Narrow · <40 None

Narrow moat with reinvestment efficiency as the key competitive advantage. Improving roic consistency would strengthen the moat.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 4 years of fundamental data.
PFE
35/100
No Moat
70+ Wide · 40-69 Narrow · <40 None

No durable moat detected, though reinvestment efficiency shows some competitive positioning. The business lacks consistent evidence of sustainable advantages.

Composite score measuring competitive advantage durability across four dimensions: returns above cost of capital, pricing power stability, revenue predictability, and capital efficiency. Based on 5 years of fundamental data.

Forensic Accounting

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AMGN
-2.24
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.
PFE
-2.53
Unlikely Manipulator
Above -1.78 = likely manipulator · -2.22 to -1.78 = grey zone

M-Score Trend

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Beneish's 8-variable model estimates the probability of earnings manipulation. An M-Score above -1.78 signals elevated risk — companies in this range have historically been 3-5× more likely to be manipulating earnings. Scores between -2.22 and -1.78 fall in a grey zone warranting further investigation.

Ownership Breakdown

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AMGN
Insiders 0.2%Institutions 85.2%Retail & Other 14.6%
No. of Institutional Holders3,901
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.
PFE
Insiders 0.1%Institutions 67.9%Retail & Other 32.0%
No. of Institutional Holders3,687
High insider ownership aligns management incentives with shareholders — a key signal in Buffett-style analysis. Institutional concentration can indicate smart-money conviction but also crowding risk.

High insider ownership aligns management incentives with shareholders. Institutional concentration can indicate smart-money conviction but also crowding risk.

Insider Buying Activity

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AMGN
0
Buys (3M)
0
Buys (12M)
No open market insider purchases found.
Open market purchases · includes direct & indirect ownership · excludes option exercises
PFE
0
Buys (3M)
0
Buys (12M)
BLAYLOCK RONALD E
Director
$499,072
@ $25.65 · 2025-02-13
GOTTLIEB SCOTT
Director
$28,240
@ $28.24 · 2024-10-30
Open market purchases · includes direct & indirect ownership · excludes option exercises

Open market purchases · includes direct & indirect ownership · excludes option exercises.

Insider Selling Activity

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AMGN
2
Sells (3M)
7
Sells (12M)
Total value (12M): $25.63M
SANTOS ESTEBAN
Officer
$20.77M
@ $379.12 · 2026-02-26
BUSCH MATTHEW C.
Officer
$375,790
@ $375.79 · 2026-02-19
GRYGIEL NANCY A
Officer
$1.06M
@ $337.26 · 2025-11-20
GORDON MURDO
Officer
$2.32M
@ $336.83 · 2025-11-12
KHOSLA RACHNA
Officer
$299,256
@ $336.24 · 2025-11-12
GRYGIEL NANCY A
Officer
$376,280
@ $296.99 · 2025-08-20
KHOSLA RACHNA
Officer
$434,520
@ $289.68 · 2025-06-05
BUSCH MATTHEW C.
Officer
$279,690
@ $279.69 · 2025-05-02
REESE DAVID M.
Chief Technology Officer
$10.23M
@ $301.56 · 2025-02-21
SANTOS ESTEBAN
Officer
$2.55M
@ $292.84 · 2025-02-19
MILLER DEREK
Officer
$593,934
@ $293.45 · 2025-02-19
GORDON MURDO
Officer
$2.59M
@ $294.79 · 2025-02-11
GRAHAM JONATHAN P
General Counsel
$7.34M
@ $293.12 · 2025-02-07
GRYGIEL NANCY A
Officer
$483,808
@ $304.47 · 2025-02-05
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives
PFE
0
Sells (3M)
0
Sells (12M)
DAMICO JENNIFER B.
Officer
$64,825
@ $25.93 · 2025-03-04
DAMICO JENNIFER B.
Officer
$147,714
@ $28.66 · 2024-08-13
Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives

Direct ownership only · excludes indirect, option exercises, planned (10b5-1) sales & derivatives.

🎭 Mr. Market's Mood

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AMGN
FearGreed
😐Neutral(49/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.
PFE
FearGreed
😐Neutral(54/100)

"Market is pricing this stock without strong emotion in either direction"

Composite sentiment score based on 6 market signals. Inspired by Buffett's "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

Composite sentiment score based on market signals. Inspired by Buffett’s "Mr. Market" allegory — fear = potential opportunity, greed = potential risk. Must be used alongside fundamental analysis, not in isolation.

⚖️ Buffett Signal

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AMGN
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (49)
PFE
Awaiting DCF Data

The Buffett Signal cross-references market sentiment with DCF valuation. Configure the DCF Analysis above to generate a signal.

DCF Margin of Safety: N/AMr. Market's Mood: Neutral (54)
View AMGN Full AnalysisView PFE Full Analysis
AMGN vs PFE: Which Is the Better Buy? | SafetyMargin.io